Nisin Z Production by Lactococcus lactis IO-1 Using Xylose as a Carbon Source.

Lactococcus lactis IO-1 was able to use xylose as a carbon source for nisin Z production; the yield based on sugar consumption was about 20% superior to that made with glucose under the same fermentation conditions. The optimal conditions for nisin Z production were with 4% xylose at pH 6.0 and 37°C. Addition of 0.1 M CaCl2 increased nisin Z production specifically, but not cell growth, acid production, or xylose consumption, and resulted in the maximum nisin Z activity of about 1.5 times that without CaCl2.