| Literature DB >> 27392075 |
Anne-Mai Ilumäe1, Maere Reidla1, Marina Chukhryaeva2, Mari Järve1, Helen Post1, Monika Karmin1, Lauri Saag1, Anastasiya Agdzhoyan3, Alena Kushniarevich4, Sergey Litvinov5, Natalya Ekomasova6, Kristiina Tambets1, Ene Metspalu1, Rita Khusainova7, Bayazit Yunusbayev1, Elza K Khusnutdinova8, Ludmila P Osipova9, Sardana Fedorova10, Olga Utevska11, Sergey Koshel12, Elena Balanovska13, Doron M Behar1, Oleg Balanovsky2, Toomas Kivisild14, Peter A Underhill15, Richard Villems16, Siiri Rootsi17.
Abstract
The paternal haplogroup (hg) N is distributed from southeast Asia to eastern Europe. The demographic processes that have shaped the vast extent of this major Y chromosome lineage across numerous linguistically and autosomally divergent populations have previously been unresolved. On the basis of 94 high-coverage re-sequenced Y chromosomes, we establish and date a detailed hg N phylogeny. We evaluate geographic structure by using 16 distinguishing binary markers in 1,631 hg N Y chromosomes from a collection of 6,521 samples from 56 populations. The more southerly distributed sub-clade N4 emerged before N2a1 and N3, found mostly in the north, but the latter two display more elaborate branching patterns, indicative of regional contrasts in recent expansions. In particular, a number of prominent and well-defined clades with common N3a3'6 ancestry occur in regionally dissimilar northern Eurasian populations, indicating almost simultaneous regional diversification and expansion within the last 5,000 years. This patrilineal genetic affinity is decoupled from the associated higher degree of language diversity.Entities:
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Year: 2016 PMID： 27392075 PMCID： PMC5005449 DOI： 10.1016/j.ajhg.2016.05.025
Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025