Literature DB >> 27390331

Myocardial Ischemia: Lack of Coronary Blood Flow or Myocardial Oxygen Supply/Demand Imbalance?

Gerd Heusch1.   

Abstract

Regional myocardial blood flow and contractile function in ischemic myocardium are well matched, and there is no evidence for an oxygen supply/demand imbalance. Thus, myocardial ischemia is lack of coronary blood flow with electric, functional, metabolic, and structural consequences for the myocardium. All therapeutic interventions must aim to improve blood flow to ischemic myocardium as much and as quickly as possible.
© 2016 American Heart Association, Inc.

Entities:  

Keywords:  coronary stenosis; ischemia; myocardium

Mesh：

Year:  2016        PMID： 27390331     DOI： 10.1161/CIRCRESAHA.116.308925

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


  25 in total

Review 1.  Modeling heart failure in animal models for novel drug discovery and development.

Authors:  Paul M L Janssen; Mohammad T Elnakish
Journal:  Expert Opin Drug Discov       Date:  2019-03-12       Impact factor: 6.098

2.  Myocardial ischemia: lack of coronary blood flow, myocardial oxygen supply-demand imbalance, or what?

Authors:  Gerd Heusch
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-04-19       Impact factor: 4.733

3.  Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathology.

Authors:  Ganesh V Halade; Vasundhara Kain; Kevin A Ingle
Journal:  Am J Physiol Heart Circ Physiol       Date:  2017-11-03       Impact factor: 4.733

4.  Targeting HIF-α for robust prevascularization of human cardiac organoids.

Authors:  Robert C Coyle; Ryan W Barrs; Dylan J Richards; Emma P Ladd; Donald R Menick; Ying Mei
Journal:  J Tissue Eng Regen Med       Date:  2020-12-08       Impact factor: 3.963

5.  LGR4 silence aggravates ischemic injury by modulating mitochondrial function and oxidative stress via ERK signaling pathway in H9c2 cells.

Authors:  Tao Chen; Xiangrui Qiao; Lele Cheng; Mengping Liu; Yangyang Deng; Xiaozhen Zhuo
Journal:  J Mol Histol       Date:  2021-02-09       Impact factor: 2.611

6.  CHIR99021 Augmented the Function of Late Endothelial Progenitor Cells by Preventing Replicative Senescence.

Authors:  Vinoth Kumar Rethineswaran; Da Yeon Kim; Yeon-Ju Kim; WoongBi Jang; Seung Taek Ji; Le Thi Hong Van; Ly Thanh Truong Giang; Jong Seong Ha; Jisoo Yun; Jinsup Jung; Sang-Mo Kwon
Journal:  Int J Mol Sci       Date:  2021-04-30       Impact factor: 5.923

7.  Could heart rate recovery and exercise capacity predict abnormal 99mTc-MIBI myocardial perfusion scan findings?

Authors:  Aryan Naghedi; Nasim Namiranian; Mohsen Goudarzi; Reza Nafisi Moghadam; Seid Kazem Razavi-Ratki
Journal:  Glob Cardiol Sci Pract       Date:  2021-04-30

8.  Knockdown of circular RNA circMAT2B reduces oxygen-glucose deprivation-induced inflammatory injury in H9c2 cells through up-regulating miR-133.

Authors:  Yanhui Zhu; Chengwei Zou; Yanting Jia; Haizhou Zhang; Xiaochun Ma; Jun Zhang
Journal:  Cell Cycle       Date:  2020-09-08       Impact factor: 4.534

Review 9.  Cardiac pathophysiology in sickle cell disease.

Authors:  Oluwabukola Temitope Gbotosho; Michael Taylor; Punam Malik
Journal:  J Thromb Thrombolysis       Date:  2021-03-07       Impact factor: 2.300

Review 10.  Role of ivabradine in management of stable angina in patients with different clinical profiles.

Authors:  Juan Carlos Kaski; Steffen Gloekler; Roberto Ferrari; Kim Fox; Bernard I Lévy; Michel Komajda; Panos Vardas; Paolo G Camici
Journal:  Open Heart       Date:  2018-03-09
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.