Literature DB >> 27389725

Recurrent meningioma of the scalp after 13 years.

Daniel Lee Ashmore1, Rachel Clancy1, Paul D Chumas2.   

Abstract

Meningiomas represent some of the most common types of tumour of the central nervous system. They are considered benign, with ∼1 in 1000 known to metastasise. We report a case of recurrent meningioma of the scalp 13 years following craniotomy to treat the primary. The recurrent tumour of the scalp was eventually excised 5 years later and the defect closed with an anterolateral thigh free flap in a joint procedure between the neurosurgeons and plastic surgeons. Histology of the scalp lesion confirmed a WHO grade I meningioma. Although a number of explanations for recurrent scalp meningiomas exist, the precise role of isolated genetic defects in scalp meningiomas is incomplete. The scalp meningioma in this case consisted of a complex karyotype suggestive of more aggressive disease. This case emphasises that cytogenetics may play a greater role in identifying more aggressive tumours than histology alone. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 27389725      PMCID: PMC4957005          DOI: 10.1136/bcr-2016-215418

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

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Authors:  Wenya Linda Bi; Yu Mei; Pankaj K Agarwalla; Rameen Beroukhim; Ian F Dunn
Journal:  Neurosurg Clin N Am       Date:  2016-04       Impact factor: 2.509

6.  Scalp Metastases of Recurrent Meningiomas: Aggressive Behavior or Surgical Seeding?

Authors:  Josue M Avecillas-Chasin; Javier Saceda-Gutierrez; Pedro Alonso-Lera; Ruben Garcia-Pumarino; Subhi Issa; Escarlata López; Juan A Barcia
Journal:  World Neurosurg       Date:  2015-03-09       Impact factor: 2.104

7.  A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma.

Authors:  Ayal A Aizer; Malak Abedalthagafi; Wenya Linda Bi; Margaret C Horvath; Nils D Arvold; Ossama Al-Mefty; Eudocia Q Lee; Lakshmi Nayak; Mikael L Rinne; Andrew D Norden; David A Reardon; Patrick Y Wen; Keith L Ligon; Azra H Ligon; Rameen Beroukhim; Ian F Dunn; Sandro Santagata; Brian M Alexander
Journal:  Neuro Oncol       Date:  2015-08-30       Impact factor: 12.300

  7 in total

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