Genomic and Epigenomic Landscape in Meningioma.

Meningiomas are the most common primary intracranial neoplasms in adults. Despite their prevalence, their biologic underpinnings remain incompletely described. The recent application of unbiased next-generation sequencing and epigenomic approaches has implicated a new array of candidate biomarkers and oncogenic drivers. These insights may serve to craft a molecular taxonomy for meningiomas and highlight putative therapeutic targets in an era of biology-informed precision medicine.