| Literature DB >> 27388631 |
L A Osminkina1, A A Kudryavtsev2, S V Zinovyev3, A P Sviridov4, Yu V Kargina4, K P Tamarov4, V N Nikiforov4, A V Ivanov3, A N Vasilyev4,5, V Yu Timoshenko4.
Abstract
The possibility of using mesoporous silicon nanoparticles as amplifiers (sensitizers) of therapeutic ultrasonic exposure were studied experimentally in vitro and in vivo. The combination of nanoparticles and ultrasound led to a significant inhibition of Hep-2 cancer cell proliferation and Lewis lung carcinoma growth in mice. These results indicated good prospects of using silicon nanoparticles as sensitizers for sonodynamic therapy of tumors.Entities:
Keywords: nanoparticles; sonodynamic therapy; tumor; ultrasound
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Year: 2016 PMID： 27388631 DOI： 10.1007/s10517-016-3399-x
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804