Literature DB >> 27384345

Small cell lung cancer: Time to revisit DNA-damaging chemotherapy.

Anish Thomas1, Yves Pommier2.   

Abstract

Rational use of DNA-damaging chemotherapy, with new combinations to heighten DNA replication stress, could improve outcomes in small cell lung cancer.
Copyright © 2016, American Association for the Advancement of Science.

Entities:  

Mesh：

Year:  2016        PMID： 27384345      PMCID： PMC7821960          DOI： 10.1126/scitranslmed.aaf6282

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  10 in total

1.  Genomic Instability in Human Pluripotent Stem Cells Arises from Replicative Stress and Chromosome Condensation Defects.

Authors:  Noa Lamm; Uri Ben-David; Tamar Golan-Lev; Zuzana Storchová; Nissim Benvenisty; Batsheva Kerem
Journal:  Cell Stem Cell       Date:  2015-12-05       Impact factor: 24.633

2.  ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.

Authors:  Rozenn Jossé; Scott E Martin; Rajarshi Guha; Pinar Ormanoglu; Thomas D Pfister; Philip M Reaper; Christopher S Barnes; Julie Jones; Peter Charlton; John R Pollard; Joel Morris; James H Doroshow; Yves Pommier
Journal:  Cancer Res       Date:  2014-09-30       Impact factor: 12.701

3.  Phase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors.

Authors:  Khanh Do; Deborah Wilsker; Jiuping Ji; Jennifer Zlott; Tomoko Freshwater; Robert J Kinders; Jerry Collins; Alice P Chen; James H Doroshow; Shivaani Kummar
Journal:  J Clin Oncol       Date:  2015-05-11       Impact factor: 44.544

4.  Comprehensive genomic profiles of small cell lung cancer.

Authors:  Julie George; Jing Shan Lim; Se Jin Jang; Yupeng Cun; Luka Ozretić; Gu Kong; Frauke Leenders; Xin Lu; Lynnette Fernández-Cuesta; Graziella Bosco; Christian Müller; Ilona Dahmen; Nadine S Jahchan; Kwon-Sik Park; Dian Yang; Anthony N Karnezis; Dedeepya Vaka; Angela Torres; Maia Segura Wang; Jan O Korbel; Roopika Menon; Sung-Min Chun; Deokhoon Kim; Matt Wilkerson; Neil Hayes; David Engelmann; Brigitte Pützer; Marc Bos; Sebastian Michels; Ignacija Vlasic; Danila Seidel; Berit Pinther; Philipp Schaub; Christian Becker; Janine Altmüller; Jun Yokota; Takashi Kohno; Reika Iwakawa; Koji Tsuta; Masayuki Noguchi; Thomas Muley; Hans Hoffmann; Philipp A Schnabel; Iver Petersen; Yuan Chen; Alex Soltermann; Verena Tischler; Chang-min Choi; Yong-Hee Kim; Pierre P Massion; Yong Zou; Dragana Jovanovic; Milica Kontic; Gavin M Wright; Prudence A Russell; Benjamin Solomon; Ina Koch; Michael Lindner; Lucia A Muscarella; Annamaria la Torre; John K Field; Marko Jakopovic; Jelena Knezevic; Esmeralda Castaños-Vélez; Luca Roz; Ugo Pastorino; Odd-Terje Brustugun; Marius Lund-Iversen; Erik Thunnissen; Jens Köhler; Martin Schuler; Johan Botling; Martin Sandelin; Montserrat Sanchez-Cespedes; Helga B Salvesen; Viktor Achter; Ulrich Lang; Magdalena Bogus; Peter M Schneider; Thomas Zander; Sascha Ansén; Michael Hallek; Jürgen Wolf; Martin Vingron; Yasushi Yatabe; William D Travis; Peter Nürnberg; Christian Reinhardt; Sven Perner; Lukas Heukamp; Reinhard Büttner; Stefan A Haas; Elisabeth Brambilla; Martin Peifer; Julien Sage; Roman K Thomas
Journal:  Nature       Date:  2015-07-13       Impact factor: 49.962

5.  Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.

Authors:  Lauren Averett Byers; Jing Wang; Monique B Nilsson; Junya Fujimoto; Pierre Saintigny; John Yordy; Uma Giri; Michael Peyton; You Hong Fan; Lixia Diao; Fatemeh Masrorpour; Li Shen; Wenbin Liu; Boris Duchemann; Praveen Tumula; Vikas Bhardwaj; James Welsh; Stephanie Weber; Bonnie S Glisson; Neda Kalhor; Ignacio I Wistuba; Luc Girard; Scott M Lippman; Gordon B Mills; Kevin R Coombes; John N Weinstein; John D Minna; John V Heymach
Journal:  Cancer Discov       Date:  2012-09-06       Impact factor: 39.397

6.  Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer.

Authors:  Charles M Rudin; Steffen Durinck; Eric W Stawiski; John T Poirier; Zora Modrusan; David S Shames; Emily A Bergbower; Yinghui Guan; James Shin; Joseph Guillory; Celina Sanchez Rivers; Catherine K Foo; Deepali Bhatt; Jeremy Stinson; Florian Gnad; Peter M Haverty; Robert Gentleman; Subhra Chaudhuri; Vasantharajan Janakiraman; Bijay S Jaiswal; Chaitali Parikh; Wenlin Yuan; Zemin Zhang; Hartmut Koeppen; Thomas D Wu; Howard M Stern; Robert L Yauch; Kenneth E Huffman; Diego D Paskulin; Peter B Illei; Marileila Varella-Garcia; Adi F Gazdar; Frederic J de Sauvage; Richard Bourgon; John D Minna; Malcolm V Brock; Somasekar Seshagiri
Journal:  Nat Genet       Date:  2012-09-02       Impact factor: 38.330

Review 7.  Replication stress: getting back on track.

Authors:  Matteo Berti; Alessandro Vindigni
Journal:  Nat Struct Mol Biol       Date:  2016-02       Impact factor: 15.369

Review 8.  Hallmarks of cancer: the next generation.

Authors:  Douglas Hanahan; Robert A Weinberg
Journal:  Cell       Date:  2011-03-04       Impact factor: 41.582

9.  A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations.

Authors:  Luis I Toledo; Matilde Murga; Rafal Zur; Rebeca Soria; Antonio Rodriguez; Sonia Martinez; Julen Oyarzabal; Joaquin Pastor; James R Bischoff; Oscar Fernandez-Capetillo
Journal:  Nat Struct Mol Biol       Date:  2011-05-08       Impact factor: 15.369

10.  CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonist.

Authors:  Sana Sarvi; Alison C Mackinnon; Nicolaos Avlonitis; Mark Bradley; Robert C Rintoul; Doris M Rassl; Wei Wang; Stuart J Forbes; Christopher D Gregory; Tariq Sethi
Journal:  Cancer Res       Date:  2014-01-16       Impact factor: 12.701
  10 in total
  19 in total

1.  Small cell lung cancer: updates and new concepts.

Authors:  Peter Ujhazy; O Wolf Lindwasser
Journal:  Transl Lung Cancer Res       Date:  2018-02

2.  Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study.

Authors:  Anish Thomas; Rasa Vilimas; Christopher Trindade; Rebecca Erwin-Cohen; Nitin Roper; Liqiang Xi; Venkatesh Krishnasamy; Elliot Levy; Andy Mammen; Samantha Nichols; Yuanbin Chen; Vamsidhar Velcheti; Faye Yin; Eva Szabo; Yves Pommier; Seth M Steinberg; Jane B Trepel; Mark Raffeld; Howard A Young; Javed Khan; Stephen Hewitt; Jung-Min Lee
Journal:  J Thorac Oncol       Date:  2019-05-04       Impact factor: 15.609

3.  Dependence on the MUC1-C Oncoprotein in Classic, Variant, and Non-neuroendocrine Small Cell Lung Cancer.

Authors:  Atsushi Fushimi; Yoshihiro Morimoto; Satoshi Ishikawa; Nami Yamashita; Atrayee Bhattacharya; Tatsuaki Daimon; Hasan Rajabi; Caining Jin; Masayuki Hagiwara; Yota Yasumizu; Zhou Luan; Wenhao Suo; Kwok-Kin Wong; Henry Withers; Song Liu; Mark D Long; Donald Kufe
Journal:  Mol Cancer Res       Date:  2022-09-02       Impact factor: 6.333

4.  Targeting DNA Repair to Drive Immune Responses: It's Time to Reconsider the Strategy for Clinical Translation.

Authors:  Nobuyuki Takahashi; Ira Surolia; Anish Thomas
Journal:  Clin Cancer Res       Date:  2020-02-17       Impact factor: 12.531

5.  Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress.

Authors:  Anish Thomas; Nobuyuki Takahashi; Vinodh N Rajapakse; Xiaohu Zhang; Yilun Sun; Michele Ceribelli; Kelli M Wilson; Yang Zhang; Erin Beck; Linda Sciuto; Samantha Nichols; Brian Elenbaas; Janusz Puc; Heike Dahmen; Astrid Zimmermann; Jillian Varonin; Christopher W Schultz; Sehyun Kim; Hirity Shimellis; Parth Desai; Carleen Klumpp-Thomas; Lu Chen; Jameson Travers; Crystal McKnight; Sam Michael; Zina Itkin; Sunmin Lee; Akira Yuno; Min-Jung Lee; Christophe E Redon; Jessica D Kindrick; Cody J Peer; Jun S Wei; Mirit I Aladjem; William Douglas Figg; Seth M Steinberg; Jane B Trepel; Frank T Zenke; Yves Pommier; Javed Khan; Craig J Thomas
Journal:  Cancer Cell       Date:  2021-04-12       Impact factor: 31.743

6.  Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies.

Authors:  Camille Tlemsani; Nobuyuki Takahashi; Lorinc Pongor; Vinodh N Rajapakse; Manoj Tyagi; Xinyu Wen; Grace-Ann Fasaye; Keith T Schmidt; Parth Desai; Chul Kim; Arun Rajan; Shannon Swift; Linda Sciuto; Rasa Vilimas; Santhana Webb; Samantha Nichols; William Douglas Figg; Yves Pommier; Kathleen Calzone; Seth M Steinberg; Jun S Wei; Udayan Guha; Clesson E Turner; Javed Khan; Anish Thomas
Journal:  Sci Transl Med       Date:  2021-01-27       Impact factor: 17.956

7.  Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors.

Authors:  Anish Thomas; Christophe E Redon; Linda Sciuto; Emerson Padiernos; Jiuping Ji; Min-Jung Lee; Akira Yuno; Sunmin Lee; Yiping Zhang; Lan Tran; William Yutzy; Arun Rajan; Udayan Guha; Haobin Chen; Raffit Hassan; Christine C Alewine; Eva Szabo; Susan E Bates; Robert J Kinders; Seth M Steinberg; James H Doroshow; Mirit I Aladjem; Jane B Trepel; Yves Pommier
Journal:  J Clin Oncol       Date:  2017-12-18       Impact factor: 50.717

8.  The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.

Authors:  Anette Szczepny; Kirstyn Carey; Lisa McKenzie; W Samantha N Jayasekara; Fernando Rossello; Alvaro Gonzalez-Rajal; Andrew S McCaw; Dean Popovski; Die Wang; Anthony J Sadler; Annabelle Mahar; Prudence A Russell; Gavin Wright; Rachael A McCloy; Daniel J Garama; Daniel J Gough; Stephen B Baylin; Andrew Burgess; Jason E Cain; D Neil Watkins
Journal:  Oncogene       Date:  2018-01-25       Impact factor: 9.867

Review 9.  Targeting DNA Replication Stress and DNA Double-Strand Break Repair for Optimizing SCLC Treatment.

Authors:  Xing Bian; Wenchu Lin
Journal:  Cancers (Basel)       Date:  2019-09-02       Impact factor: 6.639

10.  Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent.

Authors:  Beverly A Teicher; Thomas Silvers; Michael Selby; Rene Delosh; Julie Laudeman; Chad Ogle; Russell Reinhart; Ralph Parchment; Julia Krushkal; Dmitriy Sonkin; Larry Rubinstein; Joel Morris; David Evans
Journal:  Cancer Med       Date:  2017-08-01       Impact factor: 4.452
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