Literature DB >> 27381333

Catalase in Leishmaniinae: With me or against me?

Natalya Kraeva1, Eva Horáková2, Alexei Y Kostygov3, Luděk Kořený4, Anzhelika Butenko1, Vyacheslav Yurchenko5, Julius Lukeš6.   

Abstract

The catalase gene is a virtually ubiquitous component of the eukaryotic genomes. It is also present in the monoxenous (i.e. parasitizing solely insects) trypanosomatids of the subfamily Leishmaniinae, which have acquired the enzyme by horizontal gene transfer from a bacterium. However, as shown here, the catalase gene was secondarily lost from the genomes of all Leishmania sequenced so far. Due to the potentially key regulatory role of hydrogen peroxide in the inter-stagial transformation of Leishmania spp., this loss seems to be a necessary prerequisite for the emergence of a complex life cycle of these important human pathogens. Hence, in this group of protists, the advantages of keeping catalase were uniquely outweighed by its disadvantages.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Catalase; Gene loss; Leishmania; Trypanosomatids

Mesh：

Substances：

Year:  2016        PMID： 27381333     DOI： 10.1016/j.meegid.2016.06.054

Source DB:  PubMed          Journal:  Infect Genet Evol        ISSN： 1567-1348            Impact factor:   3.342


  13 in total

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Authors:  Alexandra Zakharova; Amanda T S Albanaz; Fred R Opperdoes; Ingrid Škodová-Sveráková; Diana Zagirova; Andreu Saura; Lˇubomíra Chmelová; Evgeny S Gerasimov; Tereza Leštinová; Tomáš Bečvář; Jovana Sádlová; Petr Volf; Julius Lukeš; Anton Horváth; Anzhelika Butenko; Vyacheslav Yurchenko
Journal:  PLoS Negl Trop Dis       Date:  2022-06-24

2.  Molecular mechanisms of thermal resistance of the insect trypanosomatid Crithidia thermophila.

Authors:  Aygul Ishemgulova; Anzhelika Butenko; Lucie Kortišová; Carolina Boucinha; Anastasiia Grybchuk-Ieremenko; Karina A Morelli; Martina Tesařová; Natalya Kraeva; Danyil Grybchuk; Tomáš Pánek; Pavel Flegontov; Julius Lukeš; Jan Votýpka; Márcio Galvão Pavan; Fred R Opperdoes; Viktoria Spodareva; Claudia M d'Avila-Levy; Alexei Yu Kostygov; Vyacheslav Yurchenko
Journal:  PLoS One       Date:  2017-03-22       Impact factor: 3.240

3.  Catalase and Ascorbate Peroxidase in Euglenozoan Protists.

Authors:  Ingrid Škodová-Sveráková; Kristína Záhonová; Barbora Bučková; Zoltán Füssy; Vyacheslav Yurchenko; Julius Lukeš
Journal:  Pathogens       Date:  2020-04-24

4.  Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei.

Authors:  Eva Doleželová; Michaela Kunzová; Mario Dejung; Michal Levin; Brian Panicucci; Clément Regnault; Christian J Janzen; Michael P Barrett; Falk Butter; Alena Zíková
Journal:  PLoS Biol       Date:  2020-06-10       Impact factor: 8.029

5.  Lacking catalase, a protistan parasite draws on its photosynthetic ancestry to complete an antioxidant repertoire with ascorbate peroxidase.

Authors:  Eric J Schott; Santiago Di Lella; Tsvetan R Bachvaroff; L Mario Amzel; Gerardo R Vasta
Journal:  BMC Evol Biol       Date:  2019-07-19       Impact factor: 3.260

Review 6.  Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases.

Authors:  Theo Battista; Gianni Colotti; Andrea Ilari; Annarita Fiorillo
Journal:  Molecules       Date:  2020-04-21       Impact factor: 4.411

7.  The Remarkable Metabolism of Vickermania ingenoplastis: Genomic Predictions.

Authors:  Fred R Opperdoes; Anzhelika Butenko; Alexandra Zakharova; Evgeny S Gerasimov; Sara L Zimmer; Julius Lukeš; Vyacheslav Yurchenko
Journal:  Pathogens       Date:  2021-01-14

8.  Catalase impairs Leishmania mexicana development and virulence.

Authors:  Jovana Sádlová; Lucie Podešvová; Tomáš Bečvář; Claretta Bianchi; Evgeny S Gerasimov; Andreu Saura; Kristýna Glanzová; Tereza Leštinová; Nadezhda S Matveeva; Ľubomíra Chmelová; Denisa Mlacovská; Tatiana Spitzová; Barbora Vojtková; Petr Volf; Vyacheslav Yurchenko; Natalya Kraeva
Journal:  Virulence       Date:  2021-12       Impact factor: 5.882

9.  If host is refractory, insistent parasite goes berserk: Trypanosomatid Blastocrithidia raabei in the dock bug Coreus marginatus.

Authors:  Alexander O Frolov; Marina N Malysheva; Anna I Ganyukova; Viktoria V Spodareva; Jana Králová; Vyacheslav Yurchenko; Alexei Y Kostygov
Journal:  PLoS One       Date:  2020-01-16       Impact factor: 3.240

10.  Genome Analysis of Endotrypanum and Porcisia spp., Closest Phylogenetic Relatives of Leishmania, Highlights the Role of Amastins in Shaping Pathogenicity.

Authors:  Amanda T S Albanaz; Evgeny S Gerasimov; Jeffrey J Shaw; Jovana Sádlová; Julius Lukeš; Petr Volf; Fred R Opperdoes; Alexei Y Kostygov; Anzhelika Butenko; Vyacheslav Yurchenko
Journal:  Genes (Basel)       Date:  2021-03-20       Impact factor: 4.096
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