Literature DB >> 27377037

Synthesis of photoactivatable azido-acyl caged oxazine fluorophores for live-cell imaging.

Andrew V Anzalone1, Zhixing Chen2, Virginia W Cornish1.   

Abstract

We report the design and synthesis of a photoactivatable azido-acyl oxazine fluorophore. Photoactivation is achieved cleanly and rapidly with UV light, producing a single fluorescent oxazine photoproduct. We demonstrate the utility of azido-acyl caged oxazines for protein specific labeling in living mammalian cells using the TMP-tag technology.

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Year:  2016        PMID: 27377037     DOI: 10.1039/c6cc04882j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Optochemical Control of Biological Processes in Cells and Animals.

Authors:  Nicholas Ankenbruck; Taylor Courtney; Yuta Naro; Alexander Deiters
Journal:  Angew Chem Int Ed Engl       Date:  2018-02-01       Impact factor: 15.336

2.  Reversible Absorption and Emission Responses of Nile Blue and Azure A Derivatives in Extreme Acidic and Basic Conditions.

Authors:  Xiu-Li Wang; Ru Sun; Wei-Jin Zhu; Xin-Long Sha; Jian-Feng Ge
Journal:  J Fluoresc       Date:  2017-02-06       Impact factor: 2.217

3.  A Cysteine-Reactive Small Photo-Crosslinker Possessing Caged-Fluorescence Properties: Binding-Site Determination of a Combinatorially-Selected Peptide by Fluorescence Imaging/Tandem Mass Spectrometry.

Authors:  Kazuki Yatabe; Masaru Hisada; Yudai Tabuchi; Masumi Taki
Journal:  Int J Mol Sci       Date:  2018-11-21       Impact factor: 5.923

4.  Oxime as a general photocage for the design of visible light photo-activatable fluorophores.

Authors:  Lushun Wang; Shichao Wang; Juan Tang; Vanessa B Espinoza; Axel Loredo; Zeru Tian; R Bruce Weisman; Han Xiao
Journal:  Chem Sci       Date:  2021-11-22       Impact factor: 9.825

5.  General Synthetic Method for Si-Fluoresceins and Si-Rhodamines.

Authors:  Jonathan B Grimm; Timothy A Brown; Ariana N Tkachuk; Luke D Lavis
Journal:  ACS Cent Sci       Date:  2017-08-09       Impact factor: 14.553

  5 in total

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