Literature DB >> 27364386

Why the study of the effects of biological sex is important. Commentary.

Georgios Kararigas1, Ute Seeland1, Maria Luisa Barcena de Arellano1, Elke Dworatzek1, Vera Regitz-Zagrosek1.   

Abstract

Biological sex significantly affects the presentation, outcome of treatment and progression of disease. However, the role of sex has yet underestimated consequences for physiology and pathology. We put forward that a better understanding of the effects of sex in pathophysiology and the underlying mechanisms is necessary. This may facilitate the identification of targets that respond to specific therapies, thereby contributing towards a more appropriate and individualised medical care for both men and women.

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Year:  2016        PMID： 27364386     DOI： 10.4415/ANN_16_02_03

Source DB:  PubMed          Journal:  Ann Ist Super Sanita        ISSN： 0021-2571            Impact factor:   1.663


  9 in total

Review 1.  Ageing, sex, and cardioprotection.

Authors:  Marisol Ruiz-Meana; Kerstin Boengler; David Garcia-Dorado; Derek J Hausenloy; Tuuli Kaambre; Georgios Kararigas; Cinzia Perrino; Rainer Schulz; Kirsti Ytrehus
Journal:  Br J Pharmacol       Date:  2020-02-03       Impact factor: 8.739

2.  Large-scale in silico identification of drugs exerting sex-specific effects in the heart.

Authors:  Changting Cui; Chuanbo Huang; Kejia Liu; Guoheng Xu; Jichun Yang; Yong Zhou; Yingmei Feng; Georgios Kararigas; Bin Geng; Qinghua Cui
Journal:  J Transl Med       Date:  2018-08-29       Impact factor: 5.531

3.  Assessment of Bones Deficient in Fibrillin-1 Microfibrils Reveals Pronounced Sex Differences.

Authors:  Lukas Altinbas; Nicole Bormann; Daniel Lehmann; Sarah Jeuthe; Dag Wulsten; Uwe Kornak; Peter N Robinson; Britt Wildemann; Georgios Kararigas
Journal:  Int J Mol Sci       Date:  2019-12-01       Impact factor: 5.923

Review 4.  Role of Biological Sex in the Cardiovascular-Gut Microbiome Axis.

Authors:  Shuangyue Li; Georgios Kararigas
Journal:  Front Cardiovasc Med       Date:  2022-01-10

Review 5.  Oestrogenic Regulation of Mitochondrial Dynamics.

Authors:  Siavash Beikoghli Kalkhoran; Georgios Kararigas
Journal:  Int J Mol Sci       Date:  2022-01-20       Impact factor: 5.923

6.  Sex-specific eNOS activity and function in human endothelial cells.

Authors:  Maria Grazia Cattaneo; Claudia Vanetti; Ilaria Decimo; Marzia Di Chio; Giuseppe Martano; Giulia Garrone; Francesco Bifari; Lucia Maria Vicentini
Journal:  Sci Rep       Date:  2017-08-29       Impact factor: 4.379

Review 7.  Editorial: New Insights into Estrogen/Estrogen Receptor Effects in the Cardiac and Skeletal Muscle.

Authors:  Dawn A Lowe; Georgios Kararigas
Journal:  Front Endocrinol (Lausanne)       Date:  2020-03-19       Impact factor: 5.555

Review 8.  Estrogen-related mechanisms in sex differences of hypertension and target organ damage.

Authors:  Andrea Rodrigues Sabbatini; Georgios Kararigas
Journal:  Biol Sex Differ       Date:  2020-06-01       Impact factor: 5.027

Review 9.  Sex-Related Effects on Cardiac Development and Disease.

Authors:  Georgios Siokatas; Ioanna Papatheodorou; Angeliki Daiou; Antigone Lazou; Konstantinos E Hatzistergos; Georgios Kararigas
Journal:  J Cardiovasc Dev Dis       Date:  2022-03-19
  9 in total

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