Literature DB >> 27363656

Cost of ventral hernia repair using biologic or synthetic mesh.

Crystal F Totten1, Daniel L Davenport2, Nicholas D Ward3, J Scott Roth2.   

Abstract

BACKGROUND: Patients undergoing ventral hernia repair (VHR) with biologic mesh (BioM) have higher hospital costs compared with synthetic mesh (SynM). This study compares 90-d pre- and post-VHR hospital costs (180-d) among BioM and SynM based on infection risk.
METHODS: This retrospective National Surgical Quality Improvement Program study matched patient perioperative risk with resource utilization cost for a consecutive series of VHR repairs. Patient infection risks, clinical and financial outcomes were compared in unmatched SynM (n = 303) and BioM (n = 72) groups. Propensity scores were used to match 35 SynM and BioM pairs of cases with similar infection risk for outcomes analysis.
RESULTS: BioM patients in the unmatched group were older with higher American Society of Anesthesiologists (ASA) and wound classification, and they more frequently underwent open repairs for recurrent hernias. Wound surgical site infections were more frequent in unmatched BioM patients (P = 0.001) as were 180-d costs ($43.8k versus $14.0k, P < 0.001). Propensity matching resulted in 31 clean cases. In these low-risk patients, wound occurrences and readmissions were identical, but 180-d costs remained higher ($31.8k versus $15.5k, P < 0.001). There were no differences in hospital 180-d diagnostic, emergency room, intensive care unit, floor, pharmacy, or therapeutic costs. However, 180-d operating room services and supply costs were higher in the BioM group ($21.1k versus $7.1k, P < 0.001).
CONCLUSIONS: BioM is used more commonly in hernia repairs involving higher wound class and ASA scores and recurrent hernias. Clinical outcomes after low-risk VHRs are similar; SynM utilization in low-risk hernia repairs was more cost-effective. Published by Elsevier Inc.

Entities:  

Keywords:  Biologic; Cost; Hernia; Mesh; Outcomes; Synthetic

Mesh:

Year:  2016        PMID: 27363656     DOI: 10.1016/j.jss.2016.02.040

Source DB:  PubMed          Journal:  J Surg Res        ISSN: 0022-4804            Impact factor:   2.192


  12 in total

1.  Ventral hernia repair with poly-4-hydroxybutyrate mesh.

Authors:  Margaret A Plymale; Daniel L Davenport; Adam Dugan; Amanda Zachem; John Scott Roth
Journal:  Surg Endosc       Date:  2017-09-15       Impact factor: 4.584

2.  Predictors of outpatient resource utilization following ventral and incisional hernia repair.

Authors:  Alex Wade; Margaret A Plymale; Daniel L Davenport; Sara E Johnson; Vashisht V Madabhushi; Erica Mastoroudis; Charlie Tancula; John Scott Roth
Journal:  Surg Endosc       Date:  2017-09-15       Impact factor: 4.584

3.  Prospective evaluation of poly-4-hydroxybutyrate mesh in CDC class I/high-risk ventral and incisional hernia repair: 18-month follow-up.

Authors:  John Scott Roth; Gary J Anthone; Don J Selzer; Benjamin K Poulose; James G Bittner; William W Hope; Raymond M Dunn; Robert G Martindale; Matthew I Goldblatt; David B Earle; John R Romanelli; Gregory J Mancini; Jacob A Greenberg; John G Linn; Eduardo Parra-Davila; Bryan J Sandler; Corey R Deeken; Guy R Voeller
Journal:  Surg Endosc       Date:  2017-10-23       Impact factor: 4.584

4.  Comparison of biological and alloplastic meshes in ventral incisional hernia repair.

Authors:  A Koscielny; S Widenmayer; T May; J Kalff; P Lingohr
Journal:  Langenbecks Arch Surg       Date:  2017-12-06       Impact factor: 3.445

5.  Doxycycline alters collagen composition following ventral hernia repair.

Authors:  Job C Tharappel; Jennifer W Harris; Crystal Totten; Brittany A Zwischenberger; John S Roth
Journal:  Surg Endosc       Date:  2016-08-12       Impact factor: 4.584

Review 6.  Biologic Mesh in Surgery: A Comprehensive Review and Meta-Analysis of Selected Outcomes in 51 Studies and 6079 Patients.

Authors:  David J Samson; Mahir Gachabayov; Rifat Latifi
Journal:  World J Surg       Date:  2021-01-08       Impact factor: 3.352

7.  Synthetic versus Biologic Mesh for Complex Open Ventral Hernia Repair: A Pilot Randomized Controlled Trial.

Authors:  Oscar A Olavarria; Karla Bernardi; Naila H Dhanani; Nicole B Lyons; John A Harvin; Stefanos G Millas; Tien C Ko; Lillian S Kao; Mike K Liang
Journal:  Surg Infect (Larchmt)       Date:  2020-12-01       Impact factor: 1.853

8.  Biologic vs Synthetic Mesh for Single-stage Repair of Contaminated Ventral Hernias: A Randomized Clinical Trial.

Authors:  Michael J Rosen; David M Krpata; Clayton C Petro; Alfredo Carbonell; Jeremy Warren; Benjamin K Poulose; Adele Costanzo; Chao Tu; Jeffrey Blatnik; Ajita S Prabhu
Journal:  JAMA Surg       Date:  2022-04-01       Impact factor: 16.681

Review 9.  Systematic review of the stage of innovation of biological mesh for complex or contaminated abdominal wall closure.

Authors:  S K Kamarajah; S J Chapman; J Glasbey; D Morton; N Smart; T Pinkney; A Bhangu
Journal:  BJS Open       Date:  2018-06-14

10.  When the Mesh Goes Away: An Analysis of Poly-4-Hydroxybutyrate Mesh for Complex Hernia Repair.

Authors:  Charles A Messa; Geoffrey Kozak; Robyn B Broach; John P Fischer
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-11-27
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