| Literature DB >> 27357055 |
Junwei Li1, Hong Xiao2, Soon Joon Yoon1, Chengbo Liu3, Drew Matsuura1, Wanyi Tai1, Liang Song4, Matthew O'Donnell5, Du Cheng6, Xiaohu Gao7.
Abstract
A stomach functional imaging technique based on photoacoustics achieves noninvasive gastric acid secretory assessment utilizing pH-responsive polyaniline nanoprobes. A testing protocol mimicking clinical practice is established using a mouse model. After imaging, the nanoprobes are excreted outside the body without inducing systematic toxicity. Further optimization and translation of this technology can help alleviate patients' suffering and side effects.Entities:
Keywords: gastric acid secretory assessment; nanoparticles; nanoprobes; photoacoustic imaging; polyaniline; stomach imaging
Mesh:
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Year: 2016 PMID: 27357055 PMCID: PMC5243149 DOI: 10.1002/smll.201601359
Source DB: PubMed Journal: Small ISSN: 1613-6810 Impact factor: 13.281