Literature DB >> 27354173

Targeted drug delivery to emphysematous lungs: Inhibition of MMPs by doxycycline loaded nanoparticles.

Vaideesh Parasaram1, Nasim Nosoudi1, Renee J LeClair2, Andrew Binks2, Naren Vyavahare3.   

Abstract

Entities:  

Keywords:  COPD; Drug delivery; Elastin; Emphysema; Lung

Mesh：

Substances：

Year:  2016        PMID： 27354173      PMCID： PMC4988062          DOI： 10.1016/j.pupt.2016.06.004

Source DB:  PubMed          Journal:  Pulm Pharmacol Ther        ISSN： 1094-5539            Impact factor:   3.410


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  55 in total

Review 1.  Chronic obstructive pulmonary disease * 12: New treatments for COPD.

Authors:  P J Barnes
Journal:  Thorax       Date:  2003-09       Impact factor: 9.139

2.  Drug delivery via the respiratory tract.

Authors:  P R Byron; J S Patton
Journal:  J Aerosol Med       Date:  1994

3.  Distribution of aerosolized particles in healthy and emphysematous rat lungs: comparison between experimental and numerical studies.

Authors:  Jessica M Oakes; Alison L Marsden; Céline Grandmont; Chantal Darquenne; Irene E Vignon-Clementel
Journal:  J Biomech       Date:  2015-01-22       Impact factor: 2.712

Review 4.  State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective.

Authors:  Rubin M Tuder; Toshinori Yoshida; Wadih Arap; Renata Pasqualini; Irina Petrache
Journal:  Proc Am Thorac Soc       Date:  2006-08

5.  Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells.

Authors:  Jian Liu; Wanfen Xiong; Lisa Baca-Regen; Hideaki Nagase; B Timothy Baxter
Journal:  J Vasc Surg       Date:  2003-12       Impact factor: 4.268

6.  Short term effects of doxycycline on matrix metalloproteinases 2 and 9.

Authors:  Nicola Fiotti; Nicola Altamura; Michèle Moretti; Stella Wassermann; Serena Zacchigna; Rossella Farra; Barbara Dapas; Lara Consoloni; Mauro Giacca; Gabriele Grassi; Carlo Giansante
Journal:  Cardiovasc Drugs Ther       Date:  2008-12-04       Impact factor: 3.727

7.  Effects of MMP-9 inhibition by doxycycline on proteome of lungs in high tidal volume mechanical ventilation-induced acute lung injury.

Authors:  Adrian Doroszko; Thomas S Hurst; Dorota Polewicz; Jolanta Sawicka; Justyna Fert-Bober; David H Johnson; Grzegorz Sawicki
Journal:  Proteome Sci       Date:  2010-01-29       Impact factor: 2.480

Review 8.  New treatments for COPD.

Authors:  Anta Ngkelo; Ian M Adcock
Journal:  Curr Opin Pharmacol       Date:  2013-04-18       Impact factor: 5.547

9.  Changes in elastic fibres in the small airways and alveoli in COPD.

Authors:  P N Black; P S T Ching; B Beaumont; S Ranasinghe; G Taylor; M J Merrilees
Journal:  Eur Respir J       Date:  2008-01-23       Impact factor: 16.671

10.  Effects of various inhalation modes on the deposition of radioactive pressurized aerosols.

Authors:  S P Newman; D Pavia; N Garland; S W Clarke
Journal:  Eur J Respir Dis Suppl       Date:  1982
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  4 in total

1.  Pentagalloyl glucose increases elastin deposition, decreases reactive oxygen species and matrix metalloproteinase activity in pulmonary fibroblasts under inflammatory conditions.

Authors:  Vaideesh Parasaram; Nasim Nosoudi; Aniqa Chowdhury; Naren Vyavahare
Journal:  Biochem Biophys Res Commun       Date:  2018-03-19       Impact factor: 3.575

Review 2.  Nanotherapeutics to Modulate the Compromised Micro-Environment for Lung Cancers and Chronic Obstructive Pulmonary Disease.

Authors:  Dhruv R Seshadri; Anand Ramamurthi
Journal:  Front Pharmacol       Date:  2018-07-16       Impact factor: 5.810

3.  Targeted delivery of pentagalloyl glucose inhibits matrix metalloproteinase activity and preserves elastin in emphysematous lungs.

Authors:  Vaideesh Parasaram; Xiaoying Wang; Pantrika Krisanarungson; Narendra Vyavahare
Journal:  Respir Res       Date:  2021-09-18

4.  Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma.

Authors:  Ahmed R Gardouh; Mohammed A Attia; Eman T Enan; Alaaeldeen M Elbahaie; Rania A Fouad; Mohamed El-Shafey; Amal M Youssef; Suliman Y Alomar; Zinab Abd-Elhady Ali; Sawsan A Zaitone; Mona K E Qushawy
Journal:  Molecules       Date:  2020-07-15       Impact factor: 4.411
  4 in total

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