Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Pivotal MicroRNAs in Melanoma: A Mini-Review.

Literature DB >> 27351922

Pivotal MicroRNAs in Melanoma: A Mini-Review.

Zhenjun Deng¹, Jingang Hao², Dongyun Lei¹, Yongjing He³, Lechun Lu^4,5, Li He⁶.

Abstract

Melanoma is a common skin cancer associated with ultraviolet light exposure and genetic variance. However, the etiology and molecular mechanisms of melanoma remain unknown. Recent studies have shown that microRNAs (miRNAs) can play key roles in the development and prognosis of this disease. In this study, we reviewed several pivotal miRNAs that may contribute to melanoma by involvement in the processes of invasion, migration, and metastasis of melanoma cells.

Entities: Disease

Mesh：

Substances：
MicroRNAs

Year: 2016 PMID： 27351922 DOI： 10.1007/s40291-016-0219-y

Source DB: PubMed Journal: Mol Diagn Ther ISSN： 1177-1062 Impact factor: 4.074

104 in total

1. MiR-26b inhibits melanoma cell proliferation and enhances apoptosis by suppressing TRAF5-mediated MAPK activation.

Authors: Meng Li; Chaoqin Long; Guilan Yang; Yang Luo; Hua Du
Journal: Biochem Biophys Res Commun Date: 2016-02-10 Impact factor: 3.575

2. MicroRNA-203 expression as a new prognostic marker of pancreatic adenocarcinoma.

Authors: Naoki Ikenaga; Kenoki Ohuchida; Kazuhiro Mizumoto; Jun Yu; Tadashi Kayashima; Hiroshi Sakai; Hayato Fujita; Kohei Nakata; Masao Tanaka
Journal: Ann Surg Oncol Date: 2010-07-22 Impact factor: 5.344

3. microRNA-21 is upregulated in malignant melanoma and influences apoptosis of melanocytic cells.

Authors: Imke Satzger; Anika Mattern; Uta Kuettler; Dirk Weinspach; Margarete Niebuhr; Alexander Kapp; Ralf Gutzmer
Journal: Exp Dermatol Date: 2012-07 Impact factor: 3.960

Review 4. MicroRNA and cutaneous melanoma: from discovery to prognosis and therapy.

Authors: Miguel F Segura; Holly S Greenwald; Doug Hanniford; Iman Osman; Eva Hernando
Journal: Carcinogenesis Date: 2012-06-12 Impact factor: 4.944

5. MicroRNA-dependent regulation of cKit in cutaneous melanoma.

Authors: O Igoucheva; V Alexeev
Journal: Biochem Biophys Res Commun Date: 2009-01-04 Impact factor: 3.575

6. Regulation of cancer aggressive features in melanoma cells by microRNAs.

Authors: Eyal Greenberg; Liat Hershkovitz; Orit Itzhaki; Steven Hajdu; Yael Nemlich; Rona Ortenberg; Nir Gefen; Liat Edry; Shira Modai; Yona Keisari; Michal J Besser; Jacob Schachter; Noam Shomron; Gal Markel
Journal: PLoS One Date: 2011-04-25 Impact factor: 3.240

7. Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans.

Authors: Loïc de Pontual; Evelyn Yao; Patrick Callier; Laurence Faivre; Valérie Drouin; Sandra Cariou; Arie Van Haeringen; David Geneviève; Alice Goldenberg; Myriam Oufadem; Sylvie Manouvrier; Arnold Munnich; Joana Alves Vidigal; Michel Vekemans; Stanislas Lyonnet; Alexandra Henrion-Caude; Andrea Ventura; Jeanne Amiel
Journal: Nat Genet Date: 2011-09-04 Impact factor: 38.330

8. Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors.

Authors: Y Xu; T Brenn; E R S Brown; V Doherty; D W Melton
Journal: Br J Cancer Date: 2012-01-05 Impact factor: 7.640

Pivotal MicroRNAs in Melanoma: A Mini-Review.

1. MiR-26b inhibits melanoma cell proliferation and enhances apoptosis by suppressing TRAF5-mediated MAPK activation.

2. MicroRNA-203 expression as a new prognostic marker of pancreatic adenocarcinoma.

3. microRNA-21 is upregulated in malignant melanoma and influences apoptosis of melanocytic cells.

Review 4. MicroRNA and cutaneous melanoma: from discovery to prognosis and therapy.

5. MicroRNA-dependent regulation of cKit in cutaneous melanoma.

6. Regulation of cancer aggressive features in melanoma cells by microRNAs.

7. Germline deletion of the miR-17∼92 cluster causes skeletal and growth defects in humans.

8. Differential expression of microRNAs during melanoma progression: miR-200c, miR-205 and miR-211 are downregulated in melanoma and act as tumour suppressors.

9. MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer.

10. miR-203 inhibits cell proliferation and migration of lung cancer cells by targeting PKCα.

1. Systematic Review and Meta-analysis of the Prognostic Significance of miRNAs in Melanoma Patients.

2. miR‑590‑5p inhibits tumor growth in malignant melanoma by suppressing YAP1 expression.