Literature DB >> 27350109

Advancements in tetronic acid chemistry. Part 2: Use as a simple precursor to privileged heterocyclic motifs.

Moaz M Abdou1, Rasha A El-Saeed2, Khaled M Elattar2, Zeynel Seferoğlu3, John Boukouvalas4.   

Abstract

This work highlights the literature of one of the most valuable moieties in the field of organic chemistry. In this review, the chemistry of tetronic acid as a simple precursor to privileged heterocyclic motifs is described. The synthetic procedures of different fused heterocycles incorporating a furan moiety are described. Fused heterocycles are classified as bicyclic, tricyclic, tetracyclic and spiro-fused pyran derivatives.

Entities:  

Keywords:  Heterocycles; Multicomponent reactions; Polycyclic systems; Tetronic acid

Mesh：

Substances：

Year:  2016        PMID： 27350109     DOI： 10.1007/s11030-016-9683-x

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  27 in total

1.  Facile synthesis of new 4-aza-podophyllotoxin analogs via microwave-assisted multi-component reactions and evaluation of their cytotoxic activity.

Authors:  Feng Shi; Xiao-Ning Zeng; Ge Zhang; Ning Ma; Bo Jiang; Shujiang Tu
Journal:  Bioorg Med Chem Lett       Date:  2011-09-29       Impact factor: 2.823

2.  Microwave-assisted multicomponent reaction in water leading to highly regioselective formation of benzo[f]azulen-1-ones.

Authors:  Shu-Liang Wang; Chuang Cheng; Fei-Yue Wu; Bo Jiang; Feng Shi; Shu-Jiang Tu; Trideep Rajale; Guigen Li
Journal:  Tetrahedron       Date:  2011-06-24       Impact factor: 2.457

3.  Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis.

Authors:  Igor V Magedov; Liliya Frolova; Madhuri Manpadi; Uma devi Bhoga; Hong Tang; Nikolai M Evdokimov; Olivia George; Kathy Hadje Georgiou; Steffen Renner; Matthäus Getlik; Tiffany L Kinnibrugh; Manuel A Fernandes; Severine Van slambrouck; Wim F A Steelant; Charles B Shuster; Snezna Rogelj; Willem A L van Otterlo; Alexander Kornienko
Journal:  J Med Chem       Date:  2011-05-26       Impact factor: 7.446

4.  Anti-inflammatory effects of methanol extract of Antrodia cinnamomea mycelia both in vitro and in vivo.

Authors:  Chi-Luan Wen; Chia-Chuan Chang; Shyh-Shyun Huang; Chao-Lin Kuo; Shih-Lan Hsu; Jeng-Shyan Deng; Guan-Jhong Huang
Journal:  J Ethnopharmacol       Date:  2011-06-16       Impact factor: 4.360

5.  Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays.

Authors:  Marina N Semenova; Alex S Kiselyov; Dmitry V Tsyganov; Leonid D Konyushkin; Sergei I Firgang; Roman V Semenov; Oleg R Malyshev; Mikhail M Raihstat; Fabian Fuchs; Anne Stielow; Margareta Lantow; Alex A Philchenkov; Michael P Zavelevich; Nikolay S Zefirov; Sergei A Kuznetsov; Victor V Semenov
Journal:  J Med Chem       Date:  2011-09-29       Impact factor: 7.446

6.  Nine constituents including six xanthone-related compounds isolated from two ascomycetes, Gelasinospora santi-florii and Emericella quadrilineata, found in a screening study focused on immunomodulatory activity.

Authors:  Haruhiro Fujimoto; Takeshi Asai; Yong-Pil Kim; Masami Ishibashi
Journal:  Chem Pharm Bull (Tokyo)       Date:  2006-04       Impact factor: 1.645

7.  Lactarane sesquiterpenoids from Lactarius subvellereus and their cytotoxicity.

Authors:  Ki Hyun Kim; Hyung Jun Noh; Sang Un Choi; Ki Moon Park; Soon-Ja Seok; Kang Ro Lee
Journal:  Bioorg Med Chem Lett       Date:  2010-08-03       Impact factor: 2.823

8.  Discovery and investigation of antiproliferative and apoptosis-inducing properties of new heterocyclic podophyllotoxin analogues accessible by a one-step multicomponent synthesis.

Authors:  Igor V Magedov; Madhuri Manpadi; Severine Van Slambrouck; Wim F A Steelant; Elena Rozhkova; Nikolai M Przheval'skii; Snezna Rogelj; Alexander Kornienko
Journal:  J Med Chem       Date:  2007-09-26       Impact factor: 7.446

9.  Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease.

Authors:  Do Thi Phuong; Chao-Mei Ma; Masao Hattori; Jong Sik Jin
Journal:  Phytother Res       Date:  2009-04       Impact factor: 5.878

10.  Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells.

Authors:  Mirko Andreoli; Marco Persico; Ajay Kumar; Nausicaa Orteca; Vineet Kumar; Antonella Pepe; Sakkarapalayam Mahalingam; Antonio E Alegria; Lella Petrella; Laima Sevciunaite; Alessia Camperchioli; Marisa Mariani; Antonio Di Dato; Ettore Novellino; Giovanni Scambia; Sanjay V Malhotra; Cristiano Ferlini; Caterina Fattorusso
Journal:  J Med Chem       Date:  2014-09-26       Impact factor: 7.446
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  3 in total

Review 1.  Malononitrile dimer as a privileged reactant in design and skeletal diverse synthesis of heterocyclic motifs.

Authors:  Ahmad Shaabani; Seyyed Emad Hooshmand
Journal:  Mol Divers       Date:  2018-01-03       Impact factor: 2.943

2.  Multifunctional Aspects of the Synthesized Pyrazoline Derivatives for AP1 5L X60 Steel Protection Against MIC and Acidization: Electrochemical, In Silico, and SRB Insights.

Authors:  Mohamed A Abbas; Ahmed M Eid; Moaz M Abdou; Amr Elgendy; Rasha A El-Saeed; Elsayed G Zaki
Journal:  ACS Omega       Date:  2021-03-19

Review 3.  3-(Bromoacetyl)coumarins: unraveling their synthesis, chemistry, and applications.

Authors:  Moaz M Abdou; Ahmed Abu-Rayyan; Ahmed G Bedir; S Abdel-Fattah; A M A Omar; Abdullah A Ahmed; El-Sayed I El-Desoky; Eslam A Ghaith
Journal:  RSC Adv       Date:  2021-11-29       Impact factor: 3.361
  3 in total

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