Literature DB >> 27347213

Considerations arising from requests from patients for a bilateral mastectomy who are eligible for breast-conserving surgery: Factors weighing for and against performing the operation.

Alessandro Fancellu1.   

Abstract

Rates of mastectomy and contralateral prophylactic mastectomy (CPM) are increasing in patients with unilateral breast cancer who would be candidates for receiving breast-conserving surgery, according to recent studies. One reason for this finding is the entitlement of patients to choose to undergo a bilateral mastectomy as a surgery option. The present case report details the case of a 52-year-old woman, eligible for breast conservation, who had no high risk of developing a contralateral breast cancer, but who asked for a bilateral mastectomy and immediate reconstruction instead of breast-conserving surgery. The request for a bilateral mastectomy was declined on the basis that it would be unnecessary for the patient, and an excessive intervention; the patient subsequently obtained an independent second opinion, and she underwent a bilateral mastectomy with implant reconstruction prior to receiving wound care and follow-up at our institution. At follow-up 1 year later, the patient complained of sensations of general discomfort, sexual difficulties and a loss of sensation in the nipples. On the basis of the clinical outcomes of the bilateral mastectomy and the patient's experience of the operation, the present case study highlights a need for surgeons to clearly inform patients presenting with unilateral breast cancer about the attendant risks and real benefits of bilateral mastectomy, in order to reach a mutual decision in terms of health care that is not fuelled by anxiety or an overestimation of the risk of developing secondary cancer. Bilateral mastectomy should be attentively evaluated as an option only in patients with a higher-than-average risk of developing contralateral breast cancer.

Entities:  

Keywords:  breast conserving surgery; patients' choice; prophylactic bilateral mastectomy

Year:  2016        PMID: 27347213      PMCID: PMC4907275          DOI: 10.3892/ol.2016.4641

Source DB:  PubMed          Journal:  Oncol Lett        ISSN: 1792-1074            Impact factor:   2.967


  15 in total

1.  Local Therapy Decision-Making and Contralateral Prophylactic Mastectomy in Young Women with Early-Stage Breast Cancer.

Authors:  Shoshana M Rosenberg; Karen Sepucha; Kathryn J Ruddy; Rulla M Tamimi; Shari Gelber; Meghan E Meyer; Lidia Schapira; Steven E Come; Virginia F Borges; Mehra Golshan; Eric P Winer; Ann H Partridge
Journal:  Ann Surg Oncol       Date:  2015-05-01       Impact factor: 5.344

Review 2.  Meta-analysis of the effect of preoperative breast MRI on the surgical management of ductal carcinoma in situ.

Authors:  A Fancellu; R M Turner; J M Dixon; A Pinna; P Cottu; N Houssami
Journal:  Br J Surg       Date:  2015-04-28       Impact factor: 6.939

3.  Rise of mastectomy.

Authors:  Pamela R Portschy; Todd M Tuttle
Journal:  J Surg Oncol       Date:  2013-05       Impact factor: 3.454

4.  Nationwide trends in mastectomy for early-stage breast cancer.

Authors:  Kristy L Kummerow; Liping Du; David F Penson; Yu Shyr; Mary A Hooks
Journal:  JAMA Surg       Date:  2015-01       Impact factor: 14.766

5.  Nipple-sparing mastectomy in breast cancer patients: The role of adjuvant radiotherapy (Review).

Authors:  Stefan Janssen; Edna Holz-Sapra; Dirk Rades; Alexander Moser; Gabriela Studer
Journal:  Oncol Lett       Date:  2015-03-27       Impact factor: 2.967

6.  Increase in contralateral prophylactic mastectomy: echoes of a bygone era? Surgical trends for unilateral breast cancer.

Authors:  Chee-Chee H Stucky; Richard J Gray; Nabil Wasif; Amylou C Dueck; Barbara A Pockaj
Journal:  Ann Surg Oncol       Date:  2010-09-19       Impact factor: 5.344

7.  Clinical management factors contribute to the decision for contralateral prophylactic mastectomy.

Authors:  Tari A King; Rita Sakr; Sujata Patil; Inga Gurevich; Michelle Stempel; Michelle Sampson; Monica Morrow
Journal:  J Clin Oncol       Date:  2011-04-04       Impact factor: 44.544

8.  Usefulness of magnetic resonance in patients with invasive cancer eligible for breast conservation: a comparative study.

Authors:  Alessandro Fancellu; Daniela Soro; Paolo Castiglia; Vincenzo Marras; Marcovalerio Melis; Pietrina Cottu; Alessandra Cherchi; Angela Spanu; Silvia Mulas; Claudio Pusceddu; Luca Simbula; Giovanni B Meloni
Journal:  Clin Breast Cancer       Date:  2013-10-25       Impact factor: 3.225

9.  Therapeutic nipple-sparing mastectomy: trends based on a national cancer database.

Authors:  Shailesh Agarwal; Sunil Agarwal; Leigh Neumayer; Jayant P Agarwal
Journal:  Am J Surg       Date:  2014-01-21       Impact factor: 2.565

10.  Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1.

Authors:  L C Verhoog; C T Brekelmans; C Seynaeve; L M van den Bosch; G Dahmen; A N van Geel; M M Tilanus-Linthorst; C C Bartels; A Wagner; A van den Ouweland; P Devilee; E J Meijers-Heijboer; J G Klijn
Journal:  Lancet       Date:  1998-01-31       Impact factor: 79.321

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  3 in total

1.  Comparing Clinicopathologic Features and Surgical Treatment of Premenopausal Breast Cancer across Italy and China: Report from a Medical Exchange Program.

Authors:  Alessandro Fancellu; Xue Yun Zhao; Pietrina Cottu; Valeria Sanna; Yuan Ping Li; Qin Zhu; Cinzia Tanda; Ying Yi Zhang; Yan Mei Lai; Giorgio Carlo Ginesu; Shu Qin Dai; Alberto Porcu
Journal:  Breast Care (Basel)       Date:  2020-01-21       Impact factor: 2.860

Review 2.  Basic Findings Regarding Breast Cancer in Korea in 2015: Data from a Breast Cancer Registry.

Authors:  Sang Yull Kang; Yoo Seok Kim; Zisun Kim; Hyun-Yul Kim; Se Kyung Lee; Kyu-Won Jung; Hyun Jo Youn
Journal:  J Breast Cancer       Date:  2018-03-23       Impact factor: 3.588

3.  Trends in breast reconstruction practices in a specialized breast tertiary referral centre.

Authors:  N O'Halloran; A Lowery; O Kalinina; K Sweeney; C Malone; R McLoughlin; J Kelly; A Hussey; M Kerin
Journal:  BJS Open       Date:  2017-11-13
  3 in total

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