Sabine Rohrmann1, Verena Katzke2, Rudolf Kaaks2. 1. Division of Chronic Disease Epidemiology, Epidemiology, Biostatistics and Prevention Institute (EBPI), University of Zurich, Zurich, Switzerland. Electronic address: sabine.rohrmann@uzh.ch. 2. Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Abstract
OBJECTIVE: To examine the prevalence of lower urinary tract symptoms (LUTS) in males of the general population. MATERIALS AND METHODS: In our analysis, we included 8627 men, 48-79 years of age, who participated in the fourth follow-up (FUP) of EPIC-Heidelberg (2007-2009) and replied to questions on LUTS. According to the International Prostate Symptom Score questionnaire, men were categorized as having mild (0-7 points), moderate (8-19 points), or severe LUTS (20-35 points). In addition, we examined progression of LUTS among 7821 men, who also participated in FUP 5 (2010-2012). RESULTS: There were 75.3% of men who reported mild, 22.0% who reported moderate, and 2.7% who reported severe LUTS. The prevalence increased with age. At FUP 4, 5.8% (mild symptoms) to 39.7% (severe LUTS) of participants reported use of any type of benign prostatic hyperplasia or LUTS medication. Nocturia, that is, getting up at night at least twice, was the most common symptom, followed by incomplete emptying of the bladder and urgency. There were 54.8% of men who reported worse LUTS in FUP 5, but 27.1% reported an improvement in symptoms. CONCLUSION: About a quarter of middle-aged and elderly men reported clinically relevant LUTS. Whereas symptoms in some men actually improve, more than half of men experience worsening of symptoms over a 3-year period in time.
OBJECTIVE: To examine the prevalence of lower urinary tract symptoms (LUTS) in males of the general population. MATERIALS AND METHODS: In our analysis, we included 8627 men, 48-79 years of age, who participated in the fourth follow-up (FUP) of EPIC-Heidelberg (2007-2009) and replied to questions on LUTS. According to the International Prostate Symptom Score questionnaire, men were categorized as having mild (0-7 points), moderate (8-19 points), or severe LUTS (20-35 points). In addition, we examined progression of LUTS among 7821 men, who also participated in FUP 5 (2010-2012). RESULTS: There were 75.3% of men who reported mild, 22.0% who reported moderate, and 2.7% who reported severe LUTS. The prevalence increased with age. At FUP 4, 5.8% (mild symptoms) to 39.7% (severe LUTS) of participants reported use of any type of benign prostatic hyperplasia or LUTS medication. Nocturia, that is, getting up at night at least twice, was the most common symptom, followed by incomplete emptying of the bladder and urgency. There were 54.8% of men who reported worse LUTS in FUP 5, but 27.1% reported an improvement in symptoms. CONCLUSION: About a quarter of middle-aged and elderly men reported clinically relevant LUTS. Whereas symptoms in some men actually improve, more than half of men experience worsening of symptoms over a 3-year period in time.
Authors: Sung Han Kim; Boram Park; Whi-An Kwon; Jae Young Joung; Ho Kyung Seo; Jinsoo Chung; Kang Hyun Lee Journal: Biomed Res Int Date: 2019-03-31 Impact factor: 3.411
Authors: Badereddin Mohamad Al-Ali; Anton Ponholzer; Herbert Augustin; Stephan Madersbacher; Karl Pummer Journal: Biomed Res Int Date: 2017-02-05 Impact factor: 3.411