Literature DB >> 27345866

DNA Damage and Aging Around the Clock.

Paula Gutierrez-Martinez1, Derrick J Rossi2, Isabel Beerman3.   

Abstract

The hematopoietic system undergoes many changes during aging, but the causes and molecular mechanisms behind these changes are not well understood. Wang et al. have recently implicated a circadian rhythm gene, Per2, as playing a role in the DNA damage response and in the expression of lymphoid genes in aged hematopoietic stem cells.
Copyright © 2016 Elsevier Ltd. All rights reserved.

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Year:  2016        PMID： 27345866      PMCID： PMC4969220          DOI： 10.1016/j.molmed.2016.06.006

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  10 in total

1.  Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.

Authors:  Isabel Beerman; Deepta Bhattacharya; Sasan Zandi; Mikael Sigvardsson; Irving L Weissman; David Bryder; Derrick J Rossi
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-18       Impact factor: 11.205

Review 2.  Stems cells and the pathways to aging and cancer.

Authors:  Derrick J Rossi; Catriona H M Jamieson; Irving L Weissman
Journal:  Cell       Date:  2008-02-22       Impact factor: 41.582

3.  Telomerase activity in hematopoietic cells is associated with self-renewal potential.

Authors:  S J Morrison; K R Prowse; P Ho; I L Weissman
Journal:  Immunity       Date:  1996-09       Impact factor: 31.745

Review 4.  Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease.

Authors:  Isabel Beerman; Derrick J Rossi
Journal:  Cell Stem Cell       Date:  2015-06-04       Impact factor: 24.633

Review 5.  The ageing haematopoietic stem cell compartment.

Authors:  Hartmut Geiger; Gerald de Haan; M Carolina Florian
Journal:  Nat Rev Immunol       Date:  2013-04-15       Impact factor: 53.106

6.  A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage.

Authors:  Jianwei Wang; Qian Sun; Yohei Morita; Hong Jiang; Alexander Gross; André Lechel; Kai Hildner; Luis Miguel Guachalla; Anne Gompf; Daniel Hartmann; Axel Schambach; Torsten Wuestefeld; Daniel Dauch; Hubert Schrezenmeier; Wolf-Karsten Hofmann; Hiromitsu Nakauchi; Zhenyu Ju; Hans A Kestler; Lars Zender; K Lenhard Rudolph
Journal:  Cell       Date:  2012-03-02       Impact factor: 41.582

7.  Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes.

Authors:  Hao A Duong; Charles J Weitz
Journal:  Nat Struct Mol Biol       Date:  2014-01-12       Impact factor: 15.369

8.  B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo.

Authors:  A Ephrussi; G M Church; S Tonegawa; W Gilbert
Journal:  Science       Date:  1985-01-11       Impact factor: 47.728

9.  Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle.

Authors:  Isabel Beerman; Jun Seita; Matthew A Inlay; Irving L Weissman; Derrick J Rossi
Journal:  Cell Stem Cell       Date:  2014-05-08       Impact factor: 24.633

10.  Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.

Authors:  Johanna Flach; Sietske T Bakker; Mary Mohrin; Pauline C Conroy; Eric M Pietras; Damien Reynaud; Silvia Alvarez; Morgan E Diolaiti; Fernando Ugarte; E Camilla Forsberg; Michelle M Le Beau; Bradley A Stohr; Juan Méndez; Ciaran G Morrison; Emmanuelle Passegué
Journal:  Nature       Date:  2014-07-30       Impact factor: 49.962
  10 in total
  1 in total

1.  REV-ERBα reduction is associated with clinicopathological features and prognosis in human gastric cancer.

Authors:  Xiaoshan Wang; Nana Wang; Xiang Wei; Haoyuan Yu; Zhengguang Wang
Journal:  Oncol Lett       Date:  2018-05-25       Impact factor: 2.967
  1 in total

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