Literature DB >> 18295583

Stems cells and the pathways to aging and cancer.

Derrick J Rossi1, Catriona H M Jamieson, Irving L Weissman.   

Abstract

The aging of tissue-specific stem cell and progenitor cell compartments is believed to be central to the decline of tissue and organ integrity and function in the elderly. Here, we examine evidence linking stem cell dysfunction to the pathophysiological conditions accompanying aging, focusing on the mechanisms underlying stem cell decline and their contribution to disease pathogenesis.

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Year:  2008        PMID： 18295583     DOI： 10.1016/j.cell.2008.01.036

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  365 in total

Review 1.  Using mice to examine p53 functions in cancer, aging, and longevity.

Authors:  Lawrence A Donehower
Journal:  Cold Spring Harb Perspect Biol       Date:  2009-11-04       Impact factor: 10.005

Review 2.  Stress and the epigenetic landscape: a link to the pathobiology of human diseases?

Authors:  Sarah E Johnstone; Stephen B Baylin
Journal:  Nat Rev Genet       Date:  2010-10-05       Impact factor: 53.242

3.  Isolation, characterization and differentiation potential of cardiac progenitor cells in adult pigs.

Authors:  A Vanelli; G Pennarossa; S Maffei; B G Galvez; G B Galvez; G Cossu; M Rahaman; F Gandolfi; T A L Brevini
Journal:  Stem Cell Rev Rep       Date:  2012-09       Impact factor: 5.739

4.  Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells.

Authors:  Raphael Ceccaldi; Kalindi Parmar; Enguerran Mouly; Marc Delord; Jung Min Kim; Marie Regairaz; Marika Pla; Nadia Vasquez; Qing-Shuo Zhang; Corinne Pondarre; Régis Peffault de Latour; Eliane Gluckman; Marina Cavazzana-Calvo; Thierry Leblanc; Jérôme Larghero; Markus Grompe; Gérard Socié; Alan D D'Andrea; Jean Soulier
Journal:  Cell Stem Cell       Date:  2012-06-07       Impact factor: 24.633

5.  Thymosin β4 for the treatment of acute stroke in aged rats.

Authors:  Daniel C Morris; Wing Lee Cheung; Richard Loi; Talan Zhang; Mei Lu; Zheng G Zhang; Michael Chopp
Journal:  Neurosci Lett       Date:  2017-08-31       Impact factor: 3.046

6.  Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.

Authors:  Wendy W Pang; John V Pluvinage; Elizabeth A Price; Kunju Sridhar; Daniel A Arber; Peter L Greenberg; Stanley L Schrier; Christopher Y Park; Irving L Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-06       Impact factor: 11.205

Review 7.  DNA damage and tissue repair: What we can learn from planaria.

Authors:  Paul G Barghouth; Manish Thiruvalluvan; Melanie LeGro; Néstor J Oviedo
Journal:  Semin Cell Dev Biol       Date:  2018-05-03       Impact factor: 7.727

8.  Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.

Authors:  Christian Isaac; Adam Wright; Arvydas Usas; Hongshuai Li; Ying Tang; Xiaodong Mu; Nicholas Greco; Qing Dong; Nam Vo; James Kang; Bing Wang; Johnny Huard
Journal:  J Orthop Res       Date:  2012-10-23       Impact factor: 3.494

9.  Cell autonomous and nonautonomous mechanisms drive hematopoietic stem/progenitor cell loss in the absence of DNA repair.

Authors:  Joon Seok Cho; Sung Ho Kook; Andria Rasile Robinson; Laura J Niedernhofer; Byeong-Chel Lee
Journal:  Stem Cells       Date:  2013-03       Impact factor: 6.277

10.  The paths of mortality: how understanding the biology of aging can help explain systems behavior of single cells.

Authors:  Matthew M Crane; Matt Kaeberlein
Journal:  Curr Opin Syst Biol       Date:  2017-12-06
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