Literature DB >> 27342865

Strategies to overcome the hurdles to treat fibrosis, a major unmet clinical need.

Jagdeep Nanchahal1, Boris Hinz2.   

Abstract

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Year:  2016        PMID： 27342865      PMCID： PMC4941454          DOI： 10.1073/pnas.1607896113

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  22 in total

Review 1.  Science gone translational: the OX40 agonist story.

Authors:  Andrew D Weinberg; Nicholas P Morris; Magdalena Kovacsovics-Bankowski; Walter J Urba; Brendan D Curti
Journal:  Immunol Rev       Date:  2011-11       Impact factor: 12.988

2.  Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target.

Authors:  Liaquat S Verjee; Jennifer S N Verhoekx; James K K Chan; Thomas Krausgruber; Vicky Nicolaidou; David Izadi; Dominique Davidson; Marc Feldmann; Kim S Midwood; Jagdeep Nanchahal
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-19       Impact factor: 11.205

3.  Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study.

Authors:  Patrick Marcellin; Edward Gane; Maria Buti; Nezam Afdhal; William Sievert; Ira M Jacobson; Mary Kay Washington; George Germanidis; John F Flaherty; Raul Aguilar Schall; Jeffrey D Bornstein; Kathryn M Kitrinos; G Mani Subramanian; John G McHutchison; E Jenny Heathcote
Journal:  Lancet       Date:  2012-12-10       Impact factor: 79.321

Review 4.  Systemic sclerosis: a prototypic multisystem fibrotic disorder.

Authors:  John Varga; David Abraham
Journal:  J Clin Invest       Date:  2007-03       Impact factor: 14.808

5.  Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis.

Authors:  F M Brennan; D Chantry; A Jackson; R Maini; M Feldmann
Journal:  Lancet       Date:  1989-07-29       Impact factor: 79.321

Review 6.  The significance of OX40 and OX40L to T-cell biology and immune disease.

Authors:  Michael Croft; Takanori So; Wei Duan; Pejman Soroosh
Journal:  Immunol Rev       Date:  2009-05       Impact factor: 12.988

Review 7.  The role of TNF superfamily members in T-cell function and diseases.

Authors:  Michael Croft
Journal:  Nat Rev Immunol       Date:  2009-04       Impact factor: 53.106

8.  OX40L blockade protects against inflammation-driven fibrosis.

Authors:  Muriel Elhai; Jérôme Avouac; Anna Maria Hoffmann-Vold; Nadira Ruzehaji; Olivia Amiar; Barbara Ruiz; Hassina Brahiti; Matthieu Ponsoye; Maxime Fréchet; Anne Burgevin; Sonia Pezet; Jérémy Sadoine; Thomas Guilbert; Carole Nicco; Hisaya Akiba; Vigo Heissmeyer; Arun Subramaniam; Robert Resnick; Øyvind Molberg; André Kahan; Gilles Chiocchia; Yannick Allanore
Journal:  Proc Natl Acad Sci U S A       Date:  2016-06-13       Impact factor: 11.205

Review 9.  Therapy for fibrotic diseases: nearing the starting line.

Authors:  Scott L Friedman; Dean Sheppard; Jeremy S Duffield; Shelia Violette
Journal:  Sci Transl Med       Date:  2013-01-09       Impact factor: 17.956

Review 10.  The myofibroblast in wound healing and fibrosis: answered and unanswered questions.

Authors:  Marie-Luce Bochaton-Piallat; Giulio Gabbiani; Boris Hinz
Journal:  F1000Res       Date:  2016-04-26
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  11 in total

Review 1.  The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis.

Authors:  Jessica Lawrence; Richard Nho
Journal:  Int J Mol Sci       Date:  2018-03-08       Impact factor: 5.923

2.  Anti-Tumour Necrosis Factor Therapy for Dupuytren's Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial.

Authors:  Jagdeep Nanchahal; Catherine Ball; Dominique Davidson; Lynn Williams; William Sones; Fiona E McCann; Marisa Cabrita; Jennifer Swettenham; Neil J Cahoon; Bethan Copsey; E Anne Francis; Peter C Taylor; Joanna Black; Vicki S Barber; Susan Dutton; Marc Feldmann; Sarah E Lamb
Journal:  EBioMedicine       Date:  2018-07-06       Impact factor: 8.143

3.  Reprogramming of profibrotic macrophages for treatment of bleomycin-induced pulmonary fibrosis.

Authors:  Fenghua Zhang; Ehab A Ayaub; Bingbing Wang; Estela Puchulu-Campanella; Yen-Hsing Li; Suraj U Hettiarachchi; Spencer D Lindeman; Qian Luo; Sasmita Rout; Madduri Srinivasarao; Abigail Cox; Konstantin Tsoyi; Cheryl Nickerson-Nutter; Ivan O Rosas; Philip S Low
Journal:  EMBO Mol Med       Date:  2020-06-29       Impact factor: 12.137

4.  Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis.

Authors:  David Izadi; Thomas B Layton; Lynn Williams; Fiona McCann; Marisa Cabrita; Ana I Espirito Santo; Weilin Xie; Marco Fritzsche; Huw Colin-York; Marc Feldmann; Kim S Midwood; Jagdeep Nanchahal
Journal:  Sci Adv       Date:  2019-12-04       Impact factor: 14.136

Review 5.  Targeting Certain Interleukins as Novel Treatment Options for Liver Fibrosis.

Authors:  Su Yeon An; Anca D Petrescu; Sharon DeMorrow
Journal:  Front Pharmacol       Date:  2021-03-24       Impact factor: 5.810

Review 6.  What do we know about managing Dupuytren's disease cost-effectively?

Authors:  Melina Dritsaki; Oliver Rivero-Arias; Alastair Gray; Catherine Ball; Jagdeep Nanchahal
Journal:  BMC Musculoskelet Disord       Date:  2018-01-25       Impact factor: 2.362

7.  Study protocol: A multi-centre, double blind, randomised, placebo-controlled, parallel group, phase II trial (RIDD) to determine the efficacy of intra-nodular injection of anti-TNF to control disease progression in early Dupuytren's disease, with an embedded dose response study.

Authors:  Jagdeep Nanchahal; Catherine Ball; Jennifer Swettenham; Susan Dutton; Vicki Barber; Joanna Black; Bethan Copsey; Melina Dritsaki; Peter Taylor; Alastair Gray; Marc Feldmann; Sarah Lamb
Journal:  Wellcome Open Res       Date:  2017-06-06

8.  Cellular census of human fibrosis defines functionally distinct stromal cell types and states.

Authors:  Thomas B Layton; Lynn Williams; Fiona McCann; Mingjun Zhang; Marco Fritzsche; Huw Colin-York; Marisa Cabrita; Michael T H Ng; Marc Feldmann; Stephen N Sansom; Dominic Furniss; Weilin Xie; Jagdeep Nanchahal
Journal:  Nat Commun       Date:  2020-06-02       Impact factor: 14.919

9.  A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease.

Authors:  Thomas B Layton; Lynn Williams; Nan Yang; Mingjun Zhang; Carl Lee; Marc Feldmann; Glenda Trujillo; Dominic Furniss; Jagdeep Nanchahal
Journal:  Proc Natl Acad Sci U S A       Date:  2022-03-23       Impact factor: 12.779

10.  Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking.

Authors:  Zhe Zhang; Meirong Bai; Guilherme Oliveira Barbosa; Andrew Chen; Yuehua Wei; Shuo Luo; Xin Wang; Bingying Wang; Tatsuya Tsukui; Hao Li; Dean Sheppard; Thomas B Kornberg; Dengke K Ma
Journal:  Sci Adv       Date:  2020-02-12       Impact factor: 14.957
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