John D Pavlus1, Brett W Carter2, Marc D Tolley3, Elaine S Keung4, Leila Khorashadi5, John P Lichtenberger6. 1. 1 Department of Radiology, Walter Reed National Military Medical Center, 8901 Rockville Pike, Bethesda, MD 20889. 2. 2 Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd. Houston, TX 77030. 3. 3 Department of Radiology, 35th Medical Group, Misawa Airbase, Japan. 4. 4 Department of Pathology, Walter Reed National Military Medical Center, Bethesda, MD. 5. 5 Department of Radiology, Mount Auburn Hospital, Cambridge, MA. 6. 6 Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD.
Abstract
OBJECTIVE: Thoracic neurogenic neoplasms may be a diagnostic challenge both clinically and radiologically, ranging from benign, incidentally discovered tumors to aggressive, symptomatic malignancies. These tumors may originate from any nervous structure within the chest and are derived from cells of the nerve sheath, autonomic ganglia, or paraganglia. The nervous anatomy of the thorax is complex, and neurogenic tumors may be found in any mediastinal compartment or in the chest wall. Furthermore, neurogenic tumors may indicate one of many syndromes, particularly when they are multiple. CONCLUSION: This article illustrates the complex anatomy of the nervous system within the chest and details important epidemiologic and pathophysiologic features as an approach to neurogenic tumors of the thorax. Key imaging features of neurogenic tumors occurring in the chest are identified, focusing on distinguishing characteristics and the relative advantages of available imaging modalities to further refine a differential diagnosis.
OBJECTIVE: Thoracic neurogenic neoplasms may be a diagnostic challenge both clinically and radiologically, ranging from benign, incidentally discovered tumors to aggressive, symptomatic malignancies. These tumors may originate from any nervous structure within the chest and are derived from cells of the nerve sheath, autonomic ganglia, or paraganglia. The nervous anatomy of the thorax is complex, and neurogenic tumors may be found in any mediastinal compartment or in the chest wall. Furthermore, neurogenic tumors may indicate one of many syndromes, particularly when they are multiple. CONCLUSION: This article illustrates the complex anatomy of the nervous system within the chest and details important epidemiologic and pathophysiologic features as an approach to neurogenic tumors of the thorax. Key imaging features of neurogenic tumors occurring in the chest are identified, focusing on distinguishing characteristics and the relative advantages of available imaging modalities to further refine a differential diagnosis.
Authors: Cornel Savu; Vasile Grigorie; Alexandru Melinte; Camelia Diaconu; Laura Iliescu; Mihai Dimitriu; Irina Balescu; Nicolae Bacalbasa Journal: In Vivo Date: 2020 Nov-Dec Impact factor: 2.155