Literature DB >> 33144463

Giant Intrathoracic Schwannoma: A Case Report.

Cornel Savu1,2, Vasile Grigorie3, Alexandru Melinte3, Camelia Diaconu2,4, Laura Iliescu2,5, Mihai Dimitriu2,6, Irina Balescu7, Nicolae Bacalbasa2,8,9.   

Abstract

BACKGROUND/AIM: Thoracic neurogenic tumors are most frequently located in the posterior part of the mediastinum or on the chest wall, along the intercostal nerves. Schwannomas are very well tolerated for a long period, until the tumor reaches a large size and compression of the neighbouring mediastinal organs, chest wall or spine appears. The purpose of this article was to present a case of a giant right forth intercostal nerve Schwannoma, completely resected by a right antero-lateral thoracotomy. In addition, intrathoracic giant neurogenic tumors are a rarity. CASE REPORT: The patient presented with only diminished tolerance to physical activity with no other obvious symptoms. Standard chest radiography revealed a well-defined opacity of subcostal intensity, occupying two thirds of the right hemithorax, forming a common body with the mediastinal shadow. Thoracic computed tomography (CT) identified a 21/11 cm solid mass that compresses the right lung and the right main bronchus with both a solid component and a central liquid area. Open surgery was performed in order to remove the tumor, which was 20.5/12.5/9 cm in size and weighed 1,830 g, well defined, with no invasion of the adjacent organs, having a solid-fibromatous aspect as well as a central necrotic area. The origin of the tumor was confirmed from the posterolateral part of the forth intercostal nerve. Pathology examination and immunohistochemistry confirmed the diagnosis of a benign Schwannoma.
CONCLUSION: Benign intrathoracic Schwannomas are asymptomatic for long periods and the main therapeutic option is complete surgical resection. The surgical approach, either open or video-assisted is dictated by the localisation of the tumor, local extension and most importantly the size of the neurogenic mass. Copyright
© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Schwannoma; anterolateral thoracotomy; dumbbell tumor; giant neurogenic tumors

Mesh:

Year:  2020        PMID: 33144463      PMCID: PMC7811636          DOI: 10.21873/invivo.12194

Source DB:  PubMed          Journal:  In Vivo        ISSN: 0258-851X            Impact factor:   2.155


  34 in total

1.  Asymptomatic giant thoracic schwannoma.

Authors:  Sanjay Kumar; Muhammad U Rafiq; Imthiaz Ahamed; Junaid Ansari; Michael E Cowen
Journal:  Ann Thorac Surg       Date:  2006-09       Impact factor: 4.330

2.  Localized Fibrous Tumor of the Pleura An Unusual Cause of Severe Hypoglycaemia. Case Report.

Authors:  A Pirvu; D Angelescu; C Savu
Journal:  Rev Med Chir Soc Med Nat Iasi       Date:  2016 Jul-Sep

Review 3.  Mediastinal tumors of peripheral nervous system origin.

Authors:  A M Marchevsky
Journal:  Semin Diagn Pathol       Date:  1999-02       Impact factor: 3.464

4.  Neurogenic tumors of the thorax.

Authors:  M E Ribet; G R Cardot
Journal:  Ann Thorac Surg       Date:  1994-10       Impact factor: 4.330

5.  Thoracoscopic resection of thoracic neurogenic tumors.

Authors:  Patrick P Han; Curtis A Dickman
Journal:  J Neurosurg       Date:  2002-04       Impact factor: 5.115

6.  Giant neurogenic tumors of mediastinum: report of two cases and literature review.

Authors:  Jingwei Wang; Jidong Yan; Shuhua Ren; Yu Guo; Yang Gao; Lijun Zhou
Journal:  Chin J Cancer Res       Date:  2013-04       Impact factor: 5.087

7.  Videothoracoscopic excision of thoracic neurogenic tumors.

Authors:  M Riquet; J Mouroux; F Pons; D Debrosse; A Dujon; M Dahan; R Jancovici
Journal:  Ann Thorac Surg       Date:  1995-10       Impact factor: 4.330

8.  A comparative study of video-assisted thoracoscopic resection versus thoracotomy for neurogenic tumours arising at the thoracic apex.

Authors:  Chenlu Yang; Deping Zhao; Xiao Zhou; Jiaan Ding; Gening Jiang
Journal:  Interact Cardiovasc Thorac Surg       Date:  2014-10-06

Review 9.  Schwannoma (neurilemoma) with malignant transformation. A rare, distinctive peripheral nerve tumor.

Authors:  J M Woodruff; A M Selig; K Crowley; P W Allen
Journal:  Am J Surg Pathol       Date:  1994-09       Impact factor: 6.394

10.  Primary intrathoracic malignant neurogenic tumor: report of three cases and comparison with benign neurogenic tumors resected at our institution.

Authors:  Takeshi Kawaguchi; Norikazu Kawai; Takashi Watanabe; Motoaki Yasukawa; Kohei Morita; Chiho Ohbayashi; Takashi Tojo
Journal:  Surg Case Rep       Date:  2015-01-28
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  1 in total

Review 1.  Lung neuroendocrine tumors: A systematic literature review (Review).

Authors:  Cornel Savu; Alexandru Melinte; Camelia Diaconu; Ovidiu Stiru; Florentina Gherghiceanu; Ștefan Dragoș Octavian Tudorica; Oana Clementina Dumitrașcu; Angelica Bratu; Irina Balescu; Nicolae Bacalbasa
Journal:  Exp Ther Med       Date:  2021-12-28       Impact factor: 2.447

  1 in total

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