Literature DB >> 27335256

Risk Factors and Outcomes of Patients Requiring a Permanent Pacemaker After Aortic Valve Replacement in the United States.

Michael P Robich1, Nicholas K Schiltz2, Douglas R Johnston1, Stephanie Mick1, Amar Krishnaswamy3, Rodrigo A Iglesias1, Dustin Hang1, Eric E Roselli1, Edward G Soltesz1.   

Abstract

INTRODUCTION: The need for permanent pacemaker implantation (PCM) following surgical aortic valve replacement (SAVR) is uncommon but can lead to increased hospital resource utilization. Using nationwide data, we sought to (1) identify hospital, patient, and procedure-level risk factors for PCM after SAVR and (2) determine incremental resource utilization.
METHODS: We identified 659,692 patients from the Nationwide Inpatient Sample database who underwent SAVR with or without coronary artery bypass grafting (CABG), mitral valvuloplasty (MVr), or mitral valve replacement (MVR) between 1998 and 2009. Patients with pre-existing pacemakers, a concomitant Maze procedure, or endocarditis were excluded. Multivariable regression analysis and propensity matching were used for comparisons of outcomes and costs.
RESULTS: Overall prevalence of PCM was 5.1% (n = 34,020; SAVR alone, 4.8%; SAVR + CABG, 4.6%; SAVR + MVr, 7.7%; SAVR + MVR, 10%). Important risk factors for PCM after SAVR were coexisting comorbidities, older age, and addition of mitral valve surgery. Hospital volume and teaching status, location, race, and sex were not associated with PCM. Among matched pairs, patients requiring PCM had lower in-hospital mortality (3.1% vs. 6.4%, p < 0.001) but longer median length of stay (12 vs. 9 days, p < 0.001) and higher hospital costs ($50,000 vs. $37,000, p < 0.001), and they were less likely to be discharged home (33% vs. 36%, p < 0.001). Factors associated with later PCM (postoperative day ≥6) included SAVR + MVR, female sex, fewer comorbidities, northeastern region, and higher hospital volume. Median hospital costs were greater ($57,000 vs. $48,000, p < 0.001) among patients whose pacemakers were implanted later.
CONCLUSIONS: PCM following SAVR is associated with lower hospital mortality, but increased cost and length of stay. doi: 10.1111/jocs.12769 (J Card Surg 2016;31:476-485).
© 2016 Wiley Periodicals, Inc.

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Year:  2016        PMID: 27335256     DOI: 10.1111/jocs.12769

Source DB:  PubMed          Journal:  J Card Surg        ISSN: 0886-0440            Impact factor:   1.620


  9 in total

1.  Need for Permanent Pacemaker After Surgical Aortic Valve Replacement Reduces Long-Term Survival.

Authors:  J Hunter Mehaffey; Nathan S Haywood; Robert B Hawkins; John A Kern; Nicholas R Teman; Irving L Kron; Leora T Yarboro; Gorav Ailawadi
Journal:  Ann Thorac Surg       Date:  2018-03-22       Impact factor: 4.330

2.  Incidence and Risk Factors for Permanent Pacemaker Implantation Following Mitral or Aortic Valve Surgery.

Authors:  Gil Moskowitz; Kimberly N Hong; Gennaro Giustino; A Marc Gillinov; Gorav Ailawadi; Joseph J DeRose; Alexander Iribarne; Alan J Moskowitz; Annetine C Gelijns; Natalia N Egorova
Journal:  J Am Coll Cardiol       Date:  2019-11-26       Impact factor: 24.094

Review 3.  Transcatheter versus surgical aortic valve replacement in severe, symptomatic aortic stenosis.

Authors:  Tsigkas Grigorios; Despotopoulos Stefanos; Makris Athanasios; Koniari Ioanna; Armylagos Stylianos; Davlouros Periklis; Hahalis George
Journal:  J Geriatr Cardiol       Date:  2018-01       Impact factor: 3.327

4.  National Trends in Utilization and In-Hospital Outcomes of Surgical Aortic Valve Replacements in Spain, 2001-2015.

Authors:  Rodrigo Jiménez-García; Napoleón Perez-Farinos; Javier de Miguel-Díez; Valentín Hernández-Barrera; Manuel Méndez-Bailón; Isabel Jimenez-Trujillo; José M de Miguel-Yanes; Ana López-de-Andrés
Journal:  Braz J Cardiovasc Surg       Date:  2020-02-01

5.  Commentary: If you start me up…I may never stop?

Authors:  Tomasz A Timek
Journal:  JTCVS Open       Date:  2021-07-22

6.  Sutureless aortic valve replacement in high-risk patients with active infective endocarditis.

Authors:  Alina Zubarevich; Arian Arjomandi Rad; Marcin Szczechowicz; Arjang Ruhparwar; Alexander Weymann
Journal:  J Thorac Dis       Date:  2022-09       Impact factor: 3.005

7.  Pacemaker implantation after aortic valve replacement: rapid-deployment Intuity® compared to conventional bioprostheses.

Authors:  Morgane Herry; Driss Laghlam; Olivier Touboul; Lee S Nguyen; Philippe Estagnasié; Alain Brusset; Pierre Squara
Journal:  Eur J Cardiothorac Surg       Date:  2020-08-01       Impact factor: 4.191

8.  Long-term Outcomes Associated With Permanent Pacemaker Implantation After Surgical Aortic Valve Replacement.

Authors:  Natalie Glaser; Michael Persson; Magnus Dalén; Ulrik Sartipy
Journal:  JAMA Netw Open       Date:  2021-07-01

9.  Sutureless aortic valve replacement in multivalve procedures.

Authors:  Alina Zubarevich; Marcin Szczechowicz; Konstantin Zhigalov; Anja Osswald; Jef Van den Eynde; Arian Arjomandi Rad; Robert Vardanyan; Daniel Wendt; Bastian Schmack; Arjang Ruhparwar; Alexander Weymann
Journal:  J Thorac Dis       Date:  2021-06       Impact factor: 2.895

  9 in total

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