Noelia Galiano-Castillo1,2, Irene Cantarero-Villanueva3,4,5, Carolina Fernández-Lao3,4,5, Angélica Ariza-García4,6, Lourdes Díaz-Rodríguez3,5,7, Rosario Del-Moral-Ávila8, Manuel Arroyo-Morales3,4,5. 1. Granada Institute for Biomedical Research, University Hospital Complex of Granada/University of Granada, Granada, Spain. noeliagaliano@ugr.es. 2. Department of Physical Therapy, University of Granada, Granada, Spain. noeliagaliano@ugr.es. 3. Granada Institute for Biomedical Research, University Hospital Complex of Granada/University of Granada, Granada, Spain. 4. Department of Physical Therapy, University of Granada, Granada, Spain. 5. Mixed University Sport and Health Institute, Granada, Spain. 6. Department of Physical Medicine and Rehabilitation, University Hospital San Cecilio, Granada, Spain. 7. Department of Nursing, University of Granada, Granada, Spain. 8. Radiotherapy Breast Oncology Unit, University Hospital Virgen de las Nieves, Granada, Spain.
Abstract
BACKGROUND: The chronicity status of breast cancer survivors suggests a growing need for cancer rehabilitation. Currently, the use of technology is a promising strategy for providing support, as reflected in the emergence of research interest in Web-based interventions in cancer survivorship. METHODS: A randomized controlled trial was conducted that included a total of 81 participants who had completed adjuvant therapy (except hormone treatment) for stage I to IIIA breast cancer. Participants were randomly assigned to an 8-week Internet-based, tailored exercise program (n = 40) or to a control group (n = 41).The instruments used at baseline, 8 weeks, and 6-month follow-up were the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire Core 30 and its breast cancer module, the Brief Pain Inventory, the handgrip dynamometer, the isometric abdominal test, the back dynamometer, the multiple sit-to-stand test, and the Piper Fatigue Scale. RESULTS: After the intervention, the telerehabilitation group had significantly improved scores for global health status, physical, role, cognitive functioning, and arm symptoms (all P < .01) as well as pain severity (P = .001) and pain interference (P = .045) compared with the control group. Significant improvements also were observed favoring the telerehabilitation group for affected and nonaffected side handgrip (both P = .006), abdominal, back and lower body strength (all P < .01), and total fatigue (P < .001). These findings were maintained after 6 months of follow-up, except for role functioning, pain severity, and nonaffected side handgrip. Analysis was based on an intention-to-treat principle. CONCLUSIONS: This program may improve adverse effects and maintain benefits in breast cancer survivors. The results of this study have encouraging implications for cancer care. Cancer 2016;122:3166-74.
RCT Entities:
BACKGROUND: The chronicity status of breast cancer survivors suggests a growing need for cancer rehabilitation. Currently, the use of technology is a promising strategy for providing support, as reflected in the emergence of research interest in Web-based interventions in cancer survivorship. METHODS: A randomized controlled trial was conducted that included a total of 81 participants who had completed adjuvant therapy (except hormone treatment) for stage I to IIIA breast cancer. Participants were randomly assigned to an 8-week Internet-based, tailored exercise program (n = 40) or to a control group (n = 41).The instruments used at baseline, 8 weeks, and 6-month follow-up were the European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire Core 30 and its breast cancer module, the Brief Pain Inventory, the handgrip dynamometer, the isometric abdominal test, the back dynamometer, the multiple sit-to-stand test, and the Piper Fatigue Scale. RESULTS: After the intervention, the telerehabilitation group had significantly improved scores for global health status, physical, role, cognitive functioning, and arm symptoms (all P < .01) as well as pain severity (P = .001) and pain interference (P = .045) compared with the control group. Significant improvements also were observed favoring the telerehabilitation group for affected and nonaffected side handgrip (both P = .006), abdominal, back and lower body strength (all P < .01), and total fatigue (P < .001). These findings were maintained after 6 months of follow-up, except for role functioning, pain severity, and nonaffected side handgrip. Analysis was based on an intention-to-treat principle. CONCLUSIONS: This program may improve adverse effects and maintain benefits in breast cancer survivors. The results of this study have encouraging implications for cancer care. Cancer 2016;122:3166-74.
Authors: Noelia Galiano-Castillo; Manuel Arroyo-Morales; Mario Lozano-Lozano; Carolina Fernández-Lao; Lydia Martín-Martín; Rosario Del-Moral-Ávila; Irene Cantarero-Villanueva Journal: Support Care Cancer Date: 2017-06-22 Impact factor: 3.603
Authors: Martina Chirra; Luca Marsili; Linsdey Wattley; Leonard L Sokol; Elizabeth Keeling; Simona Maule; Gabriele Sobrero; Carlo Alberto Artusi; Alberto Romagnolo; Maurizio Zibetti; Leonardo Lopiano; Alberto J Espay; Ahmed Z Obeidat; Aristide Merola Journal: Telemed J E Health Date: 2018-08-23 Impact factor: 3.536
Authors: Franziska Holtdirk; Anja Mehnert; Mario Weiss; Johannes Mayer; Björn Meyer; Peter Bröde; Maren Claus; Carsten Watzl Journal: PLoS One Date: 2021-05-07 Impact factor: 3.240
Authors: Mia Salans; Michelle D Tibbs; Minh-Phuong Huynh-Le; Anthony Yip; Kathryn Tringale; Roshan Karunamuni; Ronghui Xu; Anny Reyes; Anna Christina Macari; Tonya Pan-Weisz; Carrie R McDonald; Jona A Hattangadi-Gluth Journal: Int J Radiat Oncol Biol Phys Date: 2021-06-06 Impact factor: 7.038