Literature DB >> 27322767

Mechanical dyssynchrony in patients with heart failure and reduced ejection fraction: how to measure?

Mand J H Khidir1, Victoria Delgado, Nina Ajmone Marsan, Jeroen J Bax.   

Abstract

PURPOSE OF REVIEW: This article summarizes the most recent imaging techniques to assess left ventricular mechanical dyssynchrony and discusses their value to predict response to cardiac resynchronization therapy (CRT) together with assessment of myocardial scar and cardiac venous anatomy. RECENT
FINDINGS: Left ventricular mechanical dyssynchrony has been associated with prognosis of heart failure patients and has been shown to influence the efficacy of CRT. Although current guidelines do not recommend the assessment of left ventricular mechanical dyssynchrony to select heart failure patients for CRT, technological advances in echocardiography, cardiac magnetic resonance, nuclear imaging and computed tomography have provided powerful tools to characterize left ventricular mechanical dyssynchrony and predict response to CRT. Most important, these imaging techniques permit integration of additional information that is relevant for the efficacy of CRT, such as the extent and location of myocardial scar and the anatomy of the coronary sinus and tributaries where the left ventricular pacing lead may be positioned.
SUMMARY: Left ventricular mechanical dyssynchrony is an important parameter to select heart failure patients who are candidates for CRT. The integration of this parameter together with extent and location of myocardial scar and cardiac venous anatomy is a key to optimize the efficacy of CRT.

Entities:  

Mesh:

Year:  2016        PMID: 27322767     DOI: 10.1097/HCO.0000000000000314

Source DB:  PubMed          Journal:  Curr Opin Cardiol        ISSN: 0268-4705            Impact factor:   2.161


  2 in total

1.  Mechanical dyssynchrony: How do we measure it, what it means, and what we can do about it.

Authors:  Marat Fudim; Frederik Dalgaard; Mouhammad Fathallah; Ami E Iskandrian; Salvator Borges-Neto
Journal:  J Nucl Cardiol       Date:  2019-05-29       Impact factor: 5.952

2.  Rational and design of EuroCRT: an international observational study on multi-modality imaging and cardiac resynchronization therapy.

Authors:  Erwan Donal; Victoria Delgado; Julien Magne; Chiara Bucciarelli-Ducci; Christophe Leclercq; Bernard Cosyns; Marta Sitges; Thor Edvardsen; Elif Sade; Ivan Stankovic; Eustachio Agricola; Maurizio Galderisi; Patrizio Lancellotti; Alfredo Hernandez; Sven Plein; Denisa Muraru; Ehud Schwammenthal; Gerhard Hindricks; Bogdan A Popescu; Gilbert Habib
Journal:  Eur Heart J Cardiovasc Imaging       Date:  2017-10-01       Impact factor: 6.875

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.