| Literature DB >> 27316767 |
Shruthy Kuttappan1, Dennis Mathew1, Manitha B Nair2.
Abstract
Bone is a natural composite material consisting of an organic phase (collagen) and a mineral phase (calcium phosphate, especially hydroxyapatite). The strength of bone is attributed to the apatite, while the collagen fibrils are responsible for the toughness and visco-elasticity. The challenge in bone tissue engineering is to develop such biomimetic composite scaffolds, having a balance between biological and biomechanical properties. This review summarizes the current state of the field by outlining composite scaffolds made of gelatin/collagen in combination with bioactive ceramics for bone tissue engineering application.Entities:
Keywords: Biomimetic scaffolds; Bone tissue engineering; Collagen; Composite scaffolds; Gelatin
Mesh:
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Year: 2016 PMID: 27316767 DOI: 10.1016/j.ijbiomac.2016.06.043
Source DB: PubMed Journal: Int J Biol Macromol ISSN: 0141-8130 Impact factor: 6.953