Literature DB >> 27315535

Chromatin targeting: A BET inhibitor workaround.

Christopher J Burns1.   

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Year:  2016        PMID： 27315535     DOI： 10.1038/nchembio.2107

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  10 in total

1.  Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression.

Authors:  Heng-Hong Li; Andrew G Li; Hilary M Sheppard; Xuan Liu
Journal:  Mol Cell       Date:  2004-03-26       Impact factor: 17.970

Review 2.  BET domain co-regulators in obesity, inflammation and cancer.

Authors:  Anna C Belkina; Gerald V Denis
Journal:  Nat Rev Cancer       Date:  2012-06-22       Impact factor: 60.716

Review 3.  Targeting bromodomains: epigenetic readers of lysine acetylation.

Authors:  Panagis Filippakopoulos; Stefan Knapp
Journal:  Nat Rev Drug Discov       Date:  2014-04-22       Impact factor: 84.694

4.  Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.

Authors:  Sara Sdelci; Charles-Hugues Lardeau; Cynthia Tallant; Freya Klepsch; Björn Klaiber; James Bennett; Philipp Rathert; Michael Schuster; Thomas Penz; Oleg Fedorov; Giulio Superti-Furga; Christoph Bock; Johannes Zuber; Kilian V M Huber; Stefan Knapp; Susanne Müller; Stefan Kubicek
Journal:  Nat Chem Biol       Date:  2016-05-09       Impact factor: 15.040

5.  Selective inhibition of tumor oncogenes by disruption of super-enhancers.

Authors:  Jakob Lovén; Heather A Hoke; Charles Y Lin; Ashley Lau; David A Orlando; Christopher R Vakoc; James E Bradner; Tong Ihn Lee; Richard A Young
Journal:  Cell       Date:  2013-04-11       Impact factor: 41.582

6.  STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.

Authors:  Xiaohui Liu; Marina Vorontchikhina; Yuan-Liang Wang; Francesco Faiola; Ernest Martinez
Journal:  Mol Cell Biol       Date:  2007-10-29       Impact factor: 4.272

7.  A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth.

Authors:  Lei Wang; Jianjun Chang; Diana Varghese; Michael Dellinger; Subodh Kumar; Anne M Best; Julio Ruiz; Richard Bruick; Samuel Peña-Llopis; Junjie Xu; David J Babinski; Doug E Frantz; Rolf A Brekken; Amy M Quinn; Anton Simeonov; Johnny Easmon; Elisabeth D Martinez
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

8.  Druggability analysis and structural classification of bromodomain acetyl-lysine binding sites.

Authors:  Lewis R Vidler; Nathan Brown; Stefan Knapp; Swen Hoelder
Journal:  J Med Chem       Date:  2012-07-12       Impact factor: 7.446

9.  Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4.

Authors:  Michael Zengerle; Kwok-Ho Chan; Alessio Ciulli
Journal:  ACS Chem Biol       Date:  2015-06-16       Impact factor: 5.100

10.  Identification of small molecule modulators of gene transcription with anticancer activity.

Authors:  Tram Anh Tran; Jennifer Wichterman-Kouznetsova; Diana Varghese; Ruili Huang; Wenwei Huang; Matthias Becker; Christopher P Austin; James Inglese; Ronald L Johnson; Elisabeth D Martinez
Journal:  ACS Chem Biol       Date:  2014-09-16       Impact factor: 5.100
  10 in total
  1 in total

1.  Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma.

Authors:  Xiaohua Liu; Yu Zhang; Yalei Li; Juan Wang; Huaqian Ding; Wenjing Huang; Chunyong Ding; Hongchun Liu; Wenfu Tan; Ao Zhang
Journal:  Acta Pharm Sin B       Date:  2020-07-21       Impact factor: 11.413
  1 in total

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