Literature DB >> 27314073

Redefining the roles of apoptotic factors in carcinogenesis.

Xinjian Liu1, Yujun He2, Fang Li3, Qian Huang4, Takamitsu A Kato5, Russell P Hall1, Chuan-Yuan Li6.   

Abstract

In a recent study we reported that mammalian cells exposed to stress such as ionizing radiation can survive with activation of caspase-3 or caspase-7. We found that sublethal activation of the executioner caspases promotes chemical- and radiation-induced genetic instability and carcinogenesis, in contrast to their perceived roles as tumor suppressors.

Entities:  

Keywords:  Caspase-3; carcinogenesis; endonuclease G; genetic instability

Year:  2015        PMID： 27314073      PMCID： PMC4909400          DOI： 10.1080/23723556.2015.1054550

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  Phosphoinositide 3-OH kinase (PI3K) and PKB/Akt delay the onset of p53-mediated, transcriptionally dependent apoptosis.

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Journal:  J Biol Chem       Date:  1999-08-20       Impact factor: 5.157

Review 2.  The Bcl2 family: regulators of the cellular life-or-death switch.

Authors:  Suzanne Cory; Jerry M Adams
Journal:  Nat Rev Cancer       Date:  2002-09       Impact factor: 60.716

3.  Induction of apoptosis in fibroblasts by c-myc protein.

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Journal:  Cell       Date:  1992-04-03       Impact factor: 41.582

Review 4.  SOS repair hypothesis: phenomenology of an inducible DNA repair which is accompanied by mutagenesis.

Authors:  M Radman
Journal:  Basic Life Sci       Date:  1975

5.  Caspase-3 promotes genetic instability and carcinogenesis.

Authors:  Xinjian Liu; Yujun He; Fang Li; Qian Huang; Takamitsu A Kato; Russell P Hall; Chuan-Yuan Li
Journal:  Mol Cell       Date:  2015-04-09       Impact factor: 17.970

6.  CD95 promotes tumour growth.

Authors:  Lina Chen; Sun-Mi Park; Alexei V Tumanov; Annika Hau; Kenjiro Sawada; Christine Feig; Jerrold R Turner; Yang-Xin Fu; Iris L Romero; Ernst Lengyel; Marcus E Peter
Journal:  Nature       Date:  2010-05-27       Impact factor: 49.962

7.  TRAIL treatment provokes mutations in surviving cells.

Authors:  M M Lovric; C J Hawkins
Journal:  Oncogene       Date:  2010-07-19       Impact factor: 9.867

8.  Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response.

Authors:  Ho Lam Tang; Ho Man Tang; Keng Hou Mak; Shaomin Hu; Shan Shan Wang; Kit Man Wong; Chung Sing Timothy Wong; Hoi Yan Wu; Hiu Tung Law; Kan Liu; C Conover Talbot; Wan Keung Lau; Denise J Montell; Ming Chiu Fung
Journal:  Mol Biol Cell       Date:  2012-04-25       Impact factor: 4.138

9.  Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.

Authors:  Gabriel Ichim; Jonathan Lopez; Shafiq U Ahmed; Nathiya Muthalagu; Evangelos Giampazolias; M Eugenia Delgado; Martina Haller; Joel S Riley; Susan M Mason; Dimitris Athineos; Melissa J Parsons; Bert van de Kooij; Lisa Bouchier-Hayes; Anthony J Chalmers; Rogier W Rooswinkel; Andrew Oberst; Karen Blyth; Markus Rehm; Daniel J Murphy; Stephen W G Tait
Journal:  Mol Cell       Date:  2015-02-19       Impact factor: 17.970

10.  DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis.

Authors:  L A Casciola-Rosen; G J Anhalt; A Rosen
Journal:  J Exp Med       Date:  1995-12-01       Impact factor: 14.307
  10 in total
  4 in total

1.  Polymerase ζ Is Involved in Mitochondrial DNA Maintenance Processes in Concert with APE1 Activity.

Authors:  Heike Katrin Schreier; Rahel Stefanie Wiehe; Miria Ricchetti; Lisa Wiesmüller
Journal:  Genes (Basel)       Date:  2022-05-13       Impact factor: 4.141

2.  Increased protein S-nitrosylation in mitochondria: a key mechanism of exercise-induced cardioprotection.

Authors:  Doria Boulghobra; Mathilde Dubois; Béatrice Alpha-Bazin; Florence Coste; Maxime Olmos; Sandrine Gayrard; Isabelle Bornard; Gregory Meyer; Jean-Charles Gaillard; Jean Armengaud; Cyril Reboul
Journal:  Basic Res Cardiol       Date:  2021-12-23       Impact factor: 17.165

3.  Evaluation of mutagenesis, necrosis and apoptosis induced by omeprazole in stomach cells of patients with gastritis.

Authors:  Ana Maria Oliveira Ferreira da Mata; Marcia Fernanda Correia Jardim Paz; Ag-Anne Pereira Melo de Menezes; Antonielly Campinho Dos Reis; Bruna da Silva Souza; Carlos Dimas de Carvalho Sousa; Sônia Alves Machado; Thiago Soares Gondim Medeiros; Chandan Sarkar; Muhammad Torequl Islam; Javad Sharifi-Rad; Sevgi Durna Daştan; Mohammed M Alshehri; João Marcelo de Castro E Sousa; Ana Amélia de Carvalho Melo Cavalcante
Journal:  Cancer Cell Int       Date:  2022-04-18       Impact factor: 6.429

4.  Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis.

Authors:  Xuelian Chen; Lirong Zhang; Yujie Jiang; Lian Song; Yanfang Liu; Fang Cheng; Xin Fan; Xiongfeng Cao; Aihua Gong; Dongqing Wang; Haitao Zhu
Journal:  J Exp Clin Cancer Res       Date:  2018-04-03
  4 in total

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