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Literature DB >> 27314068

Dense fibrillar collagen is a master activator of invadopodia.

Abstract

Tumor stroma is characterized by abnormal accumulation of dense fibrillar collagen, which promotes tumor progression and metastasis. However, the effect of desmoplastic collagen on cells has been unclear. Our recent findings demonstrate that dense fibrillar collagen activates a novel phosphosignaling mechanism for robust induction of invadopodia in tumor cells and normal fibroblasts.

Entities: Disease

Keywords: Cell-matrix interactions; dense fibrillar collagen; desmoplasia; extracellular matrix; integrin; invadopodia; invadosomes; metastasis

Year: 2015 PMID： 27314068 PMCID： PMC4909436 DOI： 10.1080/23723556.2015.1035476

Source DB: PubMed Journal: Mol Cell Oncol ISSN： 2372-3556

10 in total

Review 1. Degrading devices: invadosomes in proteolytic cell invasion.

Authors: Stefan Linder; Christiane Wiesner; Mirko Himmel
Journal: Annu Rev Cell Dev Biol Date: 2011-07-21 Impact factor: 13.827

2. Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.

Authors: Yizeng Tu; Shan Wu; Xiaohua Shi; Ka Chen; Chuanyue Wu
Journal: Cell Date: 2003-04-04 Impact factor: 41.582

3. Integrin alpha2beta 1 (α2β1) promotes prostate cancer skeletal metastasis.

Authors: Joseph L Sottnik; Stephanie Daignault-Newton; Xiaotun Zhang; Colm Morrissey; Maha H Hussain; Evan T Keller; Christopher L Hall
Journal: Clin Exp Metastasis Date: 2012-12-15 Impact factor: 5.150

4. Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: defining the stages of invadopodia formation and function.

Authors: Vira V Artym; Ying Zhang; Françoise Seillier-Moiseiwitsch; Kenneth M Yamada; Susette C Mueller
Journal: Cancer Res Date: 2006-03-15 Impact factor: 12.701

5. Extracellular matrix rigidity promotes invadopodia activity.

Authors: Nelson R Alexander; Kevin M Branch; Aron Parekh; Emily S Clark; Izuchukwu C Iwueke; Scott A Guelcher; Alissa M Weaver
Journal: Curr Biol Date: 2008-08-21 Impact factor: 10.834

6. Multiparametric classification links tumor microenvironments with tumor cell phenotype.

Authors: Bojana Gligorijevic; Aviv Bergman; John Condeelis
Journal: PLoS Biol Date: 2014-11-11 Impact factor: 8.029

7. Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway.

Authors: Amélie Juin; Julie Di Martino; Birgit Leitinger; Elodie Henriet; Anne-Sophie Gary; Lisa Paysan; Jeremy Bomo; Georges Baffet; Cécile Gauthier-Rouvière; Jean Rosenbaum; Violaine Moreau; Frédéric Saltel
Journal: J Cell Biol Date: 2014-11-24 Impact factor: 10.539

Review 8. The regulation of MMP targeting to invadopodia during cancer metastasis.

Authors: Abitha Jacob; Rytis Prekeris
Journal: Front Cell Dev Biol Date: 2015-02-02

9. Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network.

Authors: Vira V Artym; Stephen Swatkoski; Kazue Matsumoto; Catherine B Campbell; Ryan J Petrie; Emilios K Dimitriadis; Xin Li; Susette C Mueller; Thomas H Bugge; Marjan Gucek; Kenneth M Yamada
Journal: J Cell Biol Date: 2015-02-02 Impact factor: 10.539

Review 10. Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers.

Authors: Matthew W Conklin; Patricia J Keely
Journal: Cell Adh Migr Date: 2012-05-01 Impact factor: 3.405

10 in total

3 in total

1. Integrin-Linked Kinase Links Integrin Activation to Invadopodia Function and Invasion via the p(T567)-Ezrin/NHERF1/NHE1 Pathway.

Authors: Maria Raffaella Greco; Loredana Moro; Stefania Forciniti; Khalid Alfarouk; Stefania Cannone; Rosa Angela Cardone; Stephan Joel Reshkin
Journal: Int J Mol Sci Date: 2021-02-22 Impact factor: 5.923

2. Structural centrosome aberrations promote non-cell-autonomous invasiveness.

Authors: Olivier Ganier; Dominik Schnerch; Philipp Oertle; Roderick Yh Lim; Marija Plodinec; Erich A Nigg
Journal: EMBO J Date: 2018-03-22 Impact factor: 11.598

3. Collagen Remodeling Plays a Pivotal Role in Endothelial Corneal Dystrophies.

Authors: Marcus Walckling; Rica Waterstradt; Simone Baltrusch
Journal: Invest Ophthalmol Vis Sci Date: 2020-12-01 Impact factor: 4.799

3 in total