Literature DB >> 27312165

Vaccinations and secondary immune thrombocytopenia with antiphospholipid antibodies by human papillomavirus vaccine.

Mojca Bizjak1, Or Bruck1, Darja Kanduc2, Sonja Praprotnik3, Yehuda Shoenfeld4.   

Abstract

A 13-year-old girl developed immune thrombocytopenic purpura (ITP) and concomitant positive antiphospholipid antibodies (aPL) following vaccination with a quadrivalent human papillomavirus (HPV) vaccine. During the course of a disease, she developed clinical manifestation with bleeding and she was treated with intravenous immunoglobulins. Consequently, the number of her platelets remained critically low and she was put on corticosteroids and rituximab. Since then, her platelet count remain within the normal range, but her aPL are still present. Published by Elsevier Inc.

Entities:  

Keywords:  ASIA syndrome; Antiphospholipid antibodies; Human papillomavirus; Immune thrombocytopenic purpura; Molecular mimicry; Vaccine

Mesh:

Substances:

Year:  2016        PMID: 27312165     DOI: 10.1053/j.seminhematol.2016.04.014

Source DB:  PubMed          Journal:  Semin Hematol        ISSN: 0037-1963            Impact factor:   3.851


  8 in total

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  8 in total

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