Literature DB >> 30676241

Addressing HPV vaccine myths: practical information for healthcare providers.

Robert A Bednarczyk1,2,3,4.   

Abstract

Human papillomavirus (HPV) vaccine uptake consistently lags behind that of other adolescent vaccines. In 2017, uptake of a single HPV vaccine dose and HPV vaccine series completion was 66% and 49%, respectively, compared to uptake of tetanus, diphtheria, and acellular pertussis vaccine (89%) and quadrivalent meningococcal conjugate vaccine (85%). Reasons for not vaccinating adolescents again HPV are varied, and in many cases, are rooted in commonly spread myths and misperceptions about the vaccine. In this review, we address five key myths - HPV vaccination is not effective at preventing cancer; Pap smears are sufficient to prevent cervical cancer; HPV vaccination is not safe; HPV vaccination is not needed since most infections are naturally cleared by the immune system; 11-12 years of age is too young to vaccinate. For each myth, we summarize the scientific evidence refuting the myth and provide speaking prompts for healthcare professionals to communicate about HPV vaccination.

Entities:  

Keywords:  HPV; Human papillomavirus; vaccine hesitance; vaccine misperceptions; vaccine myths

Mesh:

Substances:

Year:  2019        PMID: 30676241      PMCID: PMC6746482          DOI: 10.1080/21645515.2019.1565267

Source DB:  PubMed          Journal:  Hum Vaccin Immunother        ISSN: 2164-5515            Impact factor:   3.452


  141 in total

1.  HPV antibody levels and clinical efficacy following administration of a prophylactic quadrivalent HPV vaccine.

Authors:  Elmar A Joura; Susanne K Kjaer; Cosette M Wheeler; Kristján Sigurdsson; Ole-Erik Iversen; Mauricio Hernandez-Avila; Gonzalo Perez; Darron R Brown; Laura A Koutsky; Eng Hseon Tay; Patricia García; Kevin A Ault; Suzanne M Garland; Sepp Leodolter; Sven-Eric Olsson; Grace W K Tang; Daron G Ferris; Jorma Paavonen; Matti Lehtinen; Marc Steben; Xavier Bosch; Joakim Dillner; Robert J Kurman; Slawomir Majewski; Nubia Muñoz; Evan R Myers; Luisa L Villa; Frank J Taddeo; Christine Roberts; Amha Tadesse; Janine Bryan; Lisa C Lupinacci; Katherine E D Giacoletti; Shuang Lu; Scott Vuocolo; Teresa M Hesley; Richard M Haupt; Eliav Barr
Journal:  Vaccine       Date:  2008-10-16       Impact factor: 3.641

2.  Strongly decreased risk of genital warts after vaccination against human papillomavirus: nationwide follow-up of vaccinated and unvaccinated girls in Denmark.

Authors:  Maria Blomberg; Christian Dehlendorff; Christian Munk; Susanne K Kjaer
Journal:  Clin Infect Dis       Date:  2013-06-26       Impact factor: 9.079

3.  Use of a 2-Dose Schedule for Human Papillomavirus Vaccination - Updated Recommendations of the Advisory Committee on Immunization Practices.

Authors:  Elissa Meites; Allison Kempe; Lauri E Markowitz
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2016-12-16       Impact factor: 17.586

Review 4.  Natural history of cervical intraepithelial neoplasia: a critical review.

Authors:  A G Ostör
Journal:  Int J Gynecol Pathol       Date:  1993-04       Impact factor: 2.762

5.  Dose-Related Differences in Effectiveness of Human Papillomavirus Vaccination Against Genital Warts: A Nationwide Study of 550,000 Young Girls.

Authors:  Maria Blomberg; Christian Dehlendorff; Carsten Sand; Susanne K Kjaer
Journal:  Clin Infect Dis       Date:  2015-05-05       Impact factor: 9.079

6.  Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP).

Authors:  Jennifer L Liang; Tejpratap Tiwari; Pedro Moro; Nancy E Messonnier; Arthur Reingold; Mark Sawyer; Thomas A Clark
Journal:  MMWR Recomm Rep       Date:  2018-04-27

7.  Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP).

Authors:  Lauri E Markowitz; Eileen F Dunne; Mona Saraiya; Herschel W Lawson; Harrell Chesson; Elizabeth R Unger
Journal:  MMWR Recomm Rep       Date:  2007-03-23

8.  Human papillomavirus vaccination: recommendations of the Advisory Committee on Immunization Practices (ACIP).

Authors:  Lauri E Markowitz; Eileen F Dunne; Mona Saraiya; Harrell W Chesson; C Robinette Curtis; Julianne Gee; Joseph A Bocchini; Elizabeth R Unger
Journal:  MMWR Recomm Rep       Date:  2014-08-29

9.  End-of-study safety, immunogenicity, and efficacy of quadrivalent HPV (types 6, 11, 16, 18) recombinant vaccine in adult women 24-45 years of age.

Authors:  X Castellsagué; N Muñoz; P Pitisuttithum; D Ferris; J Monsonego; K Ault; J Luna; E Myers; S Mallary; O M Bautista; J Bryan; S Vuocolo; R M Haupt; A Saah
Journal:  Br J Cancer       Date:  2011-05-31       Impact factor: 7.640

10.  Human papillomavirus vaccination coverage among adolescents, 2007-2013, and postlicensure vaccine safety monitoring, 2006-2014--United States.

Authors:  Shannon Stokley; Jenny Jeyarajah; David Yankey; Maria Cano; Julianne Gee; Jill Roark; Robinette C Curtis; Lauri Markowitz
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2014-07-25       Impact factor: 17.586

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  16 in total

Review 1.  A systematic review of practice-, provider-, and patient-level determinants impacting Asian-Americans' human papillomavirus vaccine intention and uptake.

Authors:  Milkie Vu; Carla J Berg; Cam Escoffery; Hyun M Jang; Tien T Nguyen; Lisa Travis; Robert A Bednarczyk
Journal:  Vaccine       Date:  2020-08-20       Impact factor: 3.641

2.  Human papillomavirus (HPV) vaccine utilization among adults (18-29 years), BRFSS 2015.

Authors:  R Constance Wiener; Patricia A Findley; Chan Shen; Nilanjana Dwibedi; Usha Sambamoorthi
Journal:  Vaccine       Date:  2020-06-19       Impact factor: 3.641

Review 3.  An Integrated Approach for Preventing Oral Cavity and Oropharyngeal Cancers: Two Etiologies with Distinct and Shared Mechanisms of Carcinogenesis.

Authors:  Karam El-Bayoumy; Neil D Christensen; Jiafen Hu; Raphael Viscidi; Douglas B Stairs; Vonn Walter; Kun-Ming Chen; Yuan-Wan Sun; Joshua E Muscat; John P Richie
Journal:  Cancer Prev Res (Phila)       Date:  2020-05-20

4.  Passive Immunization with a Single Monoclonal Neutralizing Antibody Protects against Cutaneous and Mucosal Mouse Papillomavirus Infections.

Authors:  Sarah A Brendle; Jingwei Li; Nancy M Cladel; Karla K Balogh; Jennifer Booth; Debra A Shearer; Vonn Walter; Song Lu; Neil D Christensen; Danielle Covington; Jake DeBroff; Janice Milici; Yusheng Zhu; Raphael Viscidi; Jiafen Hu
Journal:  J Virol       Date:  2022-08-03       Impact factor: 6.549

5.  Practice-, provider- and patient-level facilitators of and barriers to HPV vaccine promotion and uptake in Georgia: a qualitative study of healthcare providers' perspectives.

Authors:  Milkie Vu; Adrian R King; Hyun Min Jang; Robert A Bednarczyk
Journal:  Health Educ Res       Date:  2020-12-23

Review 6.  There's Much Yet to be Done: Diverse Perspectives on HPV Vaccination.

Authors:  Gregory D Zimet; Nosayaba Osazuwa-Peters
Journal:  Hum Vaccin Immunother       Date:  2019       Impact factor: 3.452

7.  Gaps and Opportunities to Improve Prevention of Human Papillomavirus-Related Cancers.

Authors:  Irene O Aninye; J Michael Berry-Lawhorn; Paul Blumenthal; Tamika Felder; Naomi Jay; Janette Merrill; Jenna B Messman; Sarah Nielsen; Rebecca Perkins; Tami Rowen; Debbie Saslow; Connie Liu Trimble; Karen Smith-McCune
Journal:  J Womens Health (Larchmt)       Date:  2021-12-06       Impact factor: 2.681

Review 8.  Landscape of Immunotherapy Options for Colorectal Cancer: Current Knowledge and Future Perspectives beyond Immune Checkpoint Blockade.

Authors:  Alecsandra Gorzo; Diana Galos; Simona Ruxandra Volovat; Cristian Virgil Lungulescu; Claudia Burz; Daniel Sur
Journal:  Life (Basel)       Date:  2022-02-02

9.  Sexual behaviour, human papillomavirus and its vaccine: a qualitative study of adolescents and parents in Andalusia.

Authors:  María González-Cano; Francisco Garrido-Peña; Eugenia Gil-Garcia; Marta Lima-Serrano; María Dolores Cano-Caballero
Journal:  BMC Public Health       Date:  2021-07-28       Impact factor: 3.295

10.  Understanding parents' views toward the newly enacted HPV vaccine school entry policy in Puerto Rico: a qualitative study.

Authors:  Vivian Colón-López; Diana T Medina-Laabes; Roxana Soto Abreu; Olga L Díaz Miranda; Ana P Ortiz; María E Fernández; Pamela C Hull
Journal:  BMC Public Health       Date:  2021-10-25       Impact factor: 3.295

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