Literature DB >> 27308609

Deacetylation of mitofusin-2 by sirtuin-1: A critical event in cell survival after ischemia.

Lee Sooyeon1, Kristina L Go1, Jae-Sung Kim1.   

Abstract

Sirtuin-1 (SIRT1) is associated with longevity and cell survival. Recently, we unveiled a new role of SIRT1 in hepatic ischemia/reperfusion (I/R) injury and identified a novel interaction between SIRT1 and mitochondrial outer membrane protein mitofusin-2 (MFN2), in which SIRT1-dependent deacetylation of MFN2 regulates mitochondria and autophagy in the liver.

Entities:  

Keywords:  Autophagy; ischemia/reperfusion; mitochondria; mitofusin 2; sirtuin 1

Year:  2015        PMID： 27308609      PMCID： PMC4905389          DOI： 10.1080/23723556.2015.1087452

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

Review 1.  Deconvoluting the context-dependent role for autophagy in cancer.

Authors:  Eileen White
Journal:  Nat Rev Cancer       Date:  2012-04-26       Impact factor: 60.716

2.  Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner.

Authors:  T G Biel; S Lee; J A Flores-Toro; J W Dean; K L Go; M-H Lee; B K Law; M E Law; W A Dunn; I Zendejas; K E Behrns; J-S Kim
Journal:  Cell Death Differ       Date:  2015-07-17       Impact factor: 15.828

3.  Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.

Authors:  Frank Weinberg; Robert Hamanaka; William W Wheaton; Samuel Weinberg; Joy Joseph; Marcos Lopez; Balaraman Kalyanaraman; Gökhan M Mutlu; G R Scott Budinger; Navdeep S Chandel
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-26       Impact factor: 11.205

4.  Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma.

Authors:  Yuqing Lou; Rong Li; Jielin Liu; Yanwei Zhang; Xueyan Zhang; Bo Jin; Ya Liu; Zuoguang Wang; Hua Zhong; Shaojun Wen; Baohui Han
Journal:  Med Oncol       Date:  2015-03-22       Impact factor: 3.064

5.  Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth.

Authors:  Juan Chen; Bin Zhang; Nathalie Wong; Anthony W I Lo; Ka-Fai To; Anthony W H Chan; Margaret H L Ng; Cecilia Y S Ho; Suk-Hang Cheng; Paul B S Lai; Jun Yu; Ho-Keung Ng; Ming-Tat Ling; Ai-Long Huang; Xue-Fei Cai; Ben C B Ko
Journal:  Cancer Res       Date:  2011-04-28       Impact factor: 12.701

6.  Clinicopathological significance of SIRT1 expression in colorectal adenocarcinoma.

Authors:  Liang Lv; Zhanlong Shen; Jizhun Zhang; Hui Zhang; Jianqiang Dong; Yichao Yan; Fangfang Liu; Kewei Jiang; Yingjiang Ye; Shan Wang
Journal:  Med Oncol       Date:  2014-05-10       Impact factor: 3.064

Review 7.  Mitochondrial permeability transition: a common pathway to necrosis and apoptosis.

Authors:  Jae-Sung Kim; Lihua He; John J Lemasters
Journal:  Biochem Biophys Res Commun       Date:  2003-05-09       Impact factor: 3.575

8.  Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes.

Authors:  Jae-Sung Kim; Takashi Nitta; Dagmara Mohuczy; Kerri A O'Malley; Lyle L Moldawer; William A Dunn; Kevin E Behrns
Journal:  Hepatology       Date:  2008-05       Impact factor: 17.425

9.  SIRT1 expression is associated with poor prognosis of lung adenocarcinoma.

Authors:  Chong Li; Lingling Wang; Liang Zheng; Xianghong Zhan; Bin Xu; Jingting Jiang; Changping Wu
Journal:  Onco Targets Ther       Date:  2015-04-30       Impact factor: 4.147

10.  Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia.

Authors:  Jing Fan; Jurre J Kamphorst; Robin Mathew; Michelle K Chung; Eileen White; Tomer Shlomi; Joshua D Rabinowitz
Journal:  Mol Syst Biol       Date:  2013-12-03       Impact factor: 11.429
  10 in total
  8 in total

Review 1.  Mitochondria Initiate and Regulate Sarcopenia.

Authors:  Stephen E Alway; Junaith S Mohamed; Matthew J Myers
Journal:  Exerc Sport Sci Rev       Date:  2017-04       Impact factor: 6.230

2.  Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury.

Authors:  Beata Jablonska; Marcin Gierdalski; Li-Jin Chew; Teresa Hawley; Mackenzie Catron; Arturo Lichauco; Juan Cabrera-Luque; Tracy Yuen; David Rowitch; Vittorio Gallo
Journal:  Nat Commun       Date:  2016-12-19       Impact factor: 14.919

3.  Yap regulates gastric cancer survival and migration via SIRT1/Mfn2/mitophagy.

Authors:  Hongzhu Yan; Chengmin Qiu; Weiwei Sun; Minmin Gu; Feng Xiao; Jue Zou; Li Zhang
Journal:  Oncol Rep       Date:  2018-02-07       Impact factor: 3.906

Review 4.  Mitochondrial-Shaping Proteins in Cardiac Health and Disease - the Long and the Short of It!

Authors:  Sang-Bing Ong; Siavash Beikoghli Kalkhoran; Sauri Hernández-Reséndiz; Parisa Samangouei; Sang-Ging Ong; Derek John Hausenloy
Journal:  Cardiovasc Drugs Ther       Date:  2017-02       Impact factor: 3.727

Review 5.  Dietary Melatonin Supplementation Could Be a Promising Preventing/Therapeutic Approach for a Variety of Liver Diseases.

Authors:  Francesca Bonomini; Elisa Borsani; Gaia Favero; Luigi F Rodella; Rita Rezzani
Journal:  Nutrients       Date:  2018-08-21       Impact factor: 5.717

6.  Mitochondrial Content, but Not Function, Is Altered With a Multimodal Resistance Training Protocol and Adequate Protein Intake in Leucine-Supplemented Pre/Frail Women.

Authors:  Kathryn J Jacob; Vita Sonjak; Sally Spendiff; Russell T Hepple; Stéphanie Chevalier; Anna Perez; José A Morais
Journal:  Front Nutr       Date:  2021-01-22

Review 7.  Inclusion Body Myositis and Neoplasia: A Narrative Review.

Authors:  Laura Damian; Cristian Cezar Login; Carolina Solomon; Cristina Belizna; Svetlana Encica; Laura Urian; Ciprian Jurcut; Bogdan Stancu; Romana Vulturar
Journal:  Int J Mol Sci       Date:  2022-07-01       Impact factor: 6.208

8.  Alterations in mitochondrial dynamics with age-related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility.

Authors:  Jingwen Zhang; Zhibin He; Julia Fedorova; Cole Logan; Lauryn Bates; Kayla Davitt; Van Le; Jiayuan Murphy; Melissa Li; Mingyi Wang; Edward G Lakatta; Di Ren; Ji Li
Journal:  Aging Cell       Date:  2021-07-03       Impact factor: 9.304
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.