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Literature DB >> 27308573

Damaged replication forks tolerate USP7 to maintain genome stability.

Abstract

RAD18 functions to promote DNA damage tolerance (DTT), a process that ensures faithful genome duplication. Protein ubiquitylation/deubiquitylation is a critical regulatory mechanism controlling DTT. Recently, we have identified the deubiquitylating enzyme USP7 as a component of the DTT machinery that acts to protect RAD18 from proteasome-dependent degradation.

Entities: Chemical

Year: 2015 PMID： 27308573 PMCID： PMC4845244 DOI： 10.1080/23723556.2015.1063571

Source DB: PubMed Journal: Mol Cell Oncol ISSN： 2372-3556

10 in total

1. Elevated expression of Rad18 regulates melanoma cell proliferation.

Authors: Ronald P C Wong; Almass-houd Aguissa-Touré; Aijaz A Wani; Shahram Khosravi; Michal Martinka; Magdalena Martinka; Gang Li
Journal: Pigment Cell Melanoma Res Date: 2012-01-12 Impact factor: 4.693

Review 2. Competition, collaboration and coordination--determining how cells bypass DNA damage.

Authors: Julian E Sale
Journal: J Cell Sci Date: 2012-04-12 Impact factor: 5.285

3. Regulated expression and dynamic changes in subnuclear localization of mammalian Rad18 under normal and genotoxic conditions.

Authors: Sadaharu Masuyama; Satoshi Tateishi; Kentaro Yomogida; Yoshitake Nishimune; Keiichiro Suzuki; Yoshiyuki Sakuraba; Hirokazu Inoue; Michio Ogawa; Masaru Yamaizumi
Journal: Genes Cells Date: 2005-08 Impact factor: 1.891

4. The auto-ubiquitylation of E3 ubiquitin-protein ligase Chfr at G2 phase is required for accumulation of polo-like kinase 1 and mitotic entry in mammalian cells.

Authors: Jo-Sun Kim; Yong-Yea Park; Sun-Yi Park; Hyeseon Cho; Dongmin Kang; Hyeseong Cho
Journal: J Biol Chem Date: 2011-07-15 Impact factor: 5.157

5. Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination.

Authors: Shiho Miyase; Satoshi Tateishi; Kenji Watanabe; Kimio Tomita; Keiichiro Suzuki; Hirokazu Inoue; Masaru Yamaizumi
Journal: J Biol Chem Date: 2004-10-27 Impact factor: 5.157

6. M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability.

Authors: Honghui Ma; Hao Chen; Xue Guo; Zhentian Wang; Mathew E Sowa; Lijuan Zheng; Shibin Hu; Pingyao Zeng; Rui Guo; Jianbo Diao; Fei Lan; J Wade Harper; Yujiang Geno Shi; Yanhui Xu; Yang Shi
Journal: Proc Natl Acad Sci U S A Date: 2012-03-12 Impact factor: 11.205

Review 7. The multifaceted roles of USP7: new therapeutic opportunities.

Authors: Benjamin Nicholson; K G Suresh Kumar
Journal: Cell Biochem Biophys Date: 2011-06 Impact factor: 2.194

8. Molecular recognition of p53 and MDM2 by USP7/HAUSP.

Authors: Yi Sheng; Vivian Saridakis; Feroz Sarkari; Shili Duan; Tianne Wu; Cheryl H Arrowsmith; Lori Frappier
Journal: Nat Struct Mol Biol Date: 2006-02-12 Impact factor: 15.369

9. USP7 is essential for maintaining Rad18 stability and DNA damage tolerance.

Authors: A Zlatanou; S Sabbioneda; E S Miller; A Greenwalt; A Aggathanggelou; M M Maurice; A R Lehmann; T Stankovic; C Reverdy; F Colland; C Vaziri; G S Stewart
Journal: Oncogene Date: 2015-05-11 Impact factor: 9.867

10. DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis.

Authors: Michelle K Zeman; Jia-Ren Lin; Raimundo Freire; Karlene A Cimprich
Journal: J Cell Biol Date: 2014-07-14 Impact factor: 10.539