Literature DB >> 27308442

A tale of two cancers: Complete genetic analysis of chromophobe renal cell carcinoma contrasts with clear cell renal cell carcinoma.

Catherine C Fahey1, W Kimryn Rathmell2.   

Abstract

The Cancer Genome Atlas undertook a comprehensive genetic analysis of chromophobe renal cell carcinoma, the first of the rare tumor types to be analyzed. This analysis identified the putative region of origin as the distal nephron. Alterations in mitochondrial function, mtDNA mutations, and recurrent structural rearrangements within the TERT promoter region were also identified.

Entities:  

Keywords:  RCC; TERT; cancer metabolism; chromophobe renal cell carcinoma; clear cell renal cell carcinoma

Year:  2015        PMID： 27308442      PMCID： PMC4904899          DOI： 10.4161/23723556.2014.979686

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  The somatic genomic landscape of chromophobe renal cell carcinoma.

Authors:  Caleb F Davis; Christopher J Ricketts; Min Wang; Lixing Yang; Andrew D Cherniack; Hui Shen; Christian Buhay; Hyojin Kang; Sang Cheol Kim; Catherine C Fahey; Kathryn E Hacker; Gyan Bhanot; Dmitry A Gordenin; Andy Chu; Preethi H Gunaratne; Michael Biehl; Sahil Seth; Benny A Kaipparettu; Christopher A Bristow; Lawrence A Donehower; Eric M Wallen; Angela B Smith; Satish K Tickoo; Pheroze Tamboli; Victor Reuter; Laura S Schmidt; James J Hsieh; Toni K Choueiri; A Ari Hakimi; Lynda Chin; Matthew Meyerson; Raju Kucherlapati; Woong-Yang Park; A Gordon Robertson; Peter W Laird; Elizabeth P Henske; David J Kwiatkowski; Peter J Park; Margaret Morgan; Brian Shuch; Donna Muzny; David A Wheeler; W Marston Linehan; Richard A Gibbs; W Kimryn Rathmell; Chad J Creighton
Journal:  Cancer Cell       Date:  2014-08-21       Impact factor: 31.743

2.  Specific loss of chromosomes 1, 2, 6, 10, 13, 17, and 21 in chromophobe renal cell carcinomas revealed by comparative genomic hybridization.

Authors:  M R Speicher; B Schoell; S du Manoir; E Schröck; T Ried; T Cremer; S Störkel; A Kovacs; G Kovacs
Journal:  Am J Pathol       Date:  1994-08       Impact factor: 4.307

3.  Classification of renal cell carcinoma: Workgroup No. 1. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC).

Authors:  S Störkel; J N Eble; K Adlakha; M Amin; M L Blute; D G Bostwick; M Darson; B Delahunt; K Iczkowski
Journal:  Cancer       Date:  1997-09-01       Impact factor: 6.860

4.  Spectrum of somatic mitochondrial mutations in five cancers.

Authors:  Tatianna C Larman; Steven R DePalma; Angela G Hadjipanayis; Alexei Protopopov; Jianhua Zhang; Stacey B Gabriel; Lynda Chin; Christine E Seidman; Raju Kucherlapati; J G Seidman
Journal:  Proc Natl Acad Sci U S A       Date:  2012-08-13       Impact factor: 11.205

5.  Highly recurrent TERT promoter mutations in human melanoma.

Authors:  Franklin W Huang; Eran Hodis; Mary Jue Xu; Gregory V Kryukov; Lynda Chin; Levi A Garraway
Journal:  Science       Date:  2013-01-24       Impact factor: 47.728

6.  Somatic mitochondrial DNA mutations in human chromophobe renal cell carcinomas.

Authors:  Anetta Nagy; Monica Wilhelm; Farkas Sükösd; Börje Ljungberg; Gyula Kovacs
Journal:  Genes Chromosomes Cancer       Date:  2002-11       Impact factor: 5.006

7.  Of mice and men: divergence of gene expression patterns in kidney.

Authors:  Lydie Cheval; Fabien Pierrat; Rabary Rajerison; David Piquemal; Alain Doucet
Journal:  PLoS One       Date:  2012-10-03       Impact factor: 3.240

8.  Comprehensive molecular characterization of clear cell renal cell carcinoma.

Authors: 
Journal:  Nature       Date:  2013-06-23       Impact factor: 49.962

9.  Mutational processes molding the genomes of 21 breast cancers.

Authors:  Serena Nik-Zainal; Ludmil B Alexandrov; David C Wedge; Peter Van Loo; Christopher D Greenman; Keiran Raine; David Jones; Jonathan Hinton; John Marshall; Lucy A Stebbings; Andrew Menzies; Sancha Martin; Kenric Leung; Lina Chen; Catherine Leroy; Manasa Ramakrishna; Richard Rance; King Wai Lau; Laura J Mudie; Ignacio Varela; David J McBride; Graham R Bignell; Susanna L Cooke; Adam Shlien; John Gamble; Ian Whitmore; Mark Maddison; Patrick S Tarpey; Helen R Davies; Elli Papaemmanuil; Philip J Stephens; Stuart McLaren; Adam P Butler; Jon W Teague; Göran Jönsson; Judy E Garber; Daniel Silver; Penelope Miron; Aquila Fatima; Sandrine Boyault; Anita Langerød; Andrew Tutt; John W M Martens; Samuel A J R Aparicio; Åke Borg; Anne Vincent Salomon; Gilles Thomas; Anne-Lise Børresen-Dale; Andrea L Richardson; Michael S Neuberger; P Andrew Futreal; Peter J Campbell; Michael R Stratton
Journal:  Cell       Date:  2012-05-17       Impact factor: 41.582

10.  Signatures of mutational processes in human cancer.

Authors:  Ludmil B Alexandrov; Serena Nik-Zainal; David C Wedge; Samuel A J R Aparicio; Sam Behjati; Andrew V Biankin; Graham R Bignell; Niccolò Bolli; Ake Borg; Anne-Lise Børresen-Dale; Sandrine Boyault; Birgit Burkhardt; Adam P Butler; Carlos Caldas; Helen R Davies; Christine Desmedt; Roland Eils; Jórunn Erla Eyfjörd; John A Foekens; Mel Greaves; Fumie Hosoda; Barbara Hutter; Tomislav Ilicic; Sandrine Imbeaud; Marcin Imielinski; Marcin Imielinsk; Natalie Jäger; David T W Jones; David Jones; Stian Knappskog; Marcel Kool; Sunil R Lakhani; Carlos López-Otín; Sancha Martin; Nikhil C Munshi; Hiromi Nakamura; Paul A Northcott; Marina Pajic; Elli Papaemmanuil; Angelo Paradiso; John V Pearson; Xose S Puente; Keiran Raine; Manasa Ramakrishna; Andrea L Richardson; Julia Richter; Philip Rosenstiel; Matthias Schlesner; Ton N Schumacher; Paul N Span; Jon W Teague; Yasushi Totoki; Andrew N J Tutt; Rafael Valdés-Mas; Marit M van Buuren; Laura van 't Veer; Anne Vincent-Salomon; Nicola Waddell; Lucy R Yates; Jessica Zucman-Rossi; P Andrew Futreal; Ultan McDermott; Peter Lichter; Matthew Meyerson; Sean M Grimmond; Reiner Siebert; Elías Campo; Tatsuhiro Shibata; Stefan M Pfister; Peter J Campbell; Michael R Stratton
Journal:  Nature       Date:  2013-08-14       Impact factor: 49.962
  10 in total
  1 in total

1.  A Pan-Cancer Study of Somatic TERT Promoter Mutations and Amplification in 30,773 Tumors Profiled by Clinical Genomic Sequencing.

Authors:  Sounak Gupta; Chad M Vanderbilt; Yun-Te Lin; Jamal K Benhamida; Achim A Jungbluth; Satshil Rana; Amir Momeni-Boroujeni; Jason C Chang; Tiffany Mcfarlane; Paulo Salazar; Kerry Mullaney; Sumit Middha; Ahmet Zehir; Anuradha Gopalan; Tejus A Bale; Ian Ganly; Maria E Arcila; Ryma Benayed; Michael F Berger; Marc Ladanyi; Snjezana Dogan
Journal:  J Mol Diagn       Date:  2020-12-05       Impact factor: 5.568
  1 in total

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