| Literature DB >> 27307039 |
Joyce Liu1, Xuejun Zhu, Seong Jong Kim, Wenjun Zhang.
Abstract
Covering: up to 2016Antimycin-type depsipeptides are a family of natural products with great structural diversity and outstanding biological activities. These compounds have typically been isolated from actinomycetes and are generated from hybrid nonribosomal peptide synthetase (NRPS)-polyketide synthase (PKS) assembly lines. This review covers the literature on the four classes of antimycin-type depsipeptides, which differ by macrolactone ring size, and it discusses the discovery, biosynthesis, chemical synthesis, and biological activities of this family of compounds.Entities:
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Year: 2016 PMID: 27307039 DOI: 10.1039/c6np00004e
Source DB: PubMed Journal: Nat Prod Rep ISSN: 0265-0568 Impact factor: 13.423