| Literature DB >> 27304502 |
Kristan K Steffen1, Andrew Dillin2.
Abstract
As the first and most direct process influencing the proteostasis capacity of a cell, regulation of translation influences lifespan across taxa. Here we highlight some of the newly discovered means by which translational regulation affects cellular proteostasis, with a focus on mechanisms that may ultimately impinge upon the aging process.Mesh:
Substances:
Year: 2016 PMID: 27304502 DOI: 10.1016/j.cmet.2016.05.013
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287