Brian Downer1, Amit Kumar2, Hemalkumar Mehta3, Soham Al Snih2, Rebeca Wong4. 1. Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX, USA brdowner@utmb.edu. 2. Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX, USA. 3. Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA. 4. Department of Preventive Medicine and Community Health, University of Texas Medical Branch, TX, USA.
Abstract
PURPOSE: To study the effect of undiagnosed diabetes on the relationship between self-reported diabetes and cognitive impairment. METHODS: Data were from 1033 participants aged ≥60 from Wave III (2012) of the Mexican Health and Aging Study. Participants were classified as nondiabetic (n = 589), undiagnosed diabetic (n = 201), and self-reported diabetic (n = 243). Multivariate logistic regression models were used to estimate the relationship between self-reported diabetes and severity of cognitive impairment (nonimpaired, moderate impaired, severe impaired). RESULTS: Self-reported diabetes was associated with significantly higher odds for severe, but not moderate, cognitive impairment (odds ratio [OR] = 2.70, 95% confidence interval [CI] = 1.39-5.32). The association between self-reported diabetes and severe cognitive impairment decreased by 6.3% when undiagnosed diabetics were included in the nondiabetic category and by 30.4% when undiagnosed diabetics were included in the self-reported diabetes category. DISCUSSION: The association between self-reported diabetes and severe cognitive impairment is underestimated when undiagnosed diabetics are not differentiated from self-reported diabetics and nondiabetics.
PURPOSE: To study the effect of undiagnosed diabetes on the relationship between self-reported diabetes and cognitive impairment. METHODS: Data were from 1033 participants aged ≥60 from Wave III (2012) of the Mexican Health and Aging Study. Participants were classified as nondiabetic (n = 589), undiagnosed diabetic (n = 201), and self-reported diabetic (n = 243). Multivariate logistic regression models were used to estimate the relationship between self-reported diabetes and severity of cognitive impairment (nonimpaired, moderate impaired, severe impaired). RESULTS: Self-reported diabetes was associated with significantly higher odds for severe, but not moderate, cognitive impairment (odds ratio [OR] = 2.70, 95% confidence interval [CI] = 1.39-5.32). The association between self-reported diabetes and severe cognitive impairment decreased by 6.3% when undiagnosed diabetics were included in the nondiabetic category and by 30.4% when undiagnosed diabetics were included in the self-reported diabetes category. DISCUSSION: The association between self-reported diabetes and severe cognitive impairment is underestimated when undiagnosed diabetics are not differentiated from self-reported diabetics and nondiabetics.
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