| Literature DB >> 27302372 |
Luis Mansilla Alvarez1,2, Pablo Blanco1,2, Carlos Bulant1,2, Enzo Dari3, Alessandro Veneziani4, Raúl Feijóo1,2.
Abstract
In this work, we present a novel approach tailored to approximate the Navier-Stokes equations to simulate fluid flow in three-dimensional tubular domains of arbitrary cross-sectional shape. The proposed methodology is aimed at filling the gap between (cheap) one-dimensional and (expensive) three-dimensional models, featuring descriptive capabilities comparable with the full and accurate 3D description of the problem at a low computational cost. In addition, this methodology can easily be tuned or even adapted to address local features demanding more accuracy. The numerical strategy employs finite (pipe-type) elements that take advantage of the pipe structure of the spatial domain under analysis. While low order approximation is used for the longitudinal description of the physical fields, transverse approximation is enriched using high order polynomials. Although our application of interest is computational hemodynamics and its relevance to pathological dynamics like atherosclerosis, the approach is quite general and can be applied in any internal fluid dynamics problem in pipe-like domains. Numerical examples covering academic cases as well as patient-specific coronary arterial geometries demonstrate the potentialities of the developed methodology and its performance when compared against traditional finite element methods.Entities:
Keywords: coronary blood flow; hemodynamics; high order; model order reduction; patient-specific
Mesh:
Year: 2016 PMID: 27302372 DOI: 10.1002/cnm.2808
Source DB: PubMed Journal: Int J Numer Method Biomed Eng ISSN: 2040-7939 Impact factor: 2.747