Literature DB >> 2729947

Antibacterial activity of the new glycopeptide antibiotic SKF104662.

J H Jorgensen1, J S Redding, L A Maher.   

Abstract

The inhibitory activity of the new glycopeptide antibiotic SKF104662 was generally equivalent (+/- 1 concentration increment) to the activities of vancomycin, teicoplanin, and daptomycin against selected gram-positive bacteria. However, SKF104662 demonstrated greater activity against Staphylococcus epidermidis and S. haemolyticus than did teicoplanin and was more active than the other drugs against Clostridium difficile isolates. SKF104662 possessed bactericidal activity quite similar to that of vancomycin against selected isolates of Staphylococcus, Streptococcus, and Enterococcus species.

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Year:  1989        PMID： 2729947      PMCID： PMC172478          DOI： 10.1128/AAC.33.4.560

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Antimicrobial activity and spectrum of LY146032, a lipopeptide antibiotic, including susceptibility testing recommendations.

Authors:  R N Jones; A L Barry
Journal:  Antimicrob Agents Chemother       Date:  1987-04       Impact factor: 5.191

2.  In vitro and in vivo activity of LY 146032, a new cyclic lipopeptide antibiotic.

Authors:  G M Eliopoulos; S Willey; E Reiszner; P G Spitzer; G Caputo; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1986-10       Impact factor: 5.191

3.  Teicoplanin.

Authors:  A H Williams; R N Grüneberg
Journal:  J Antimicrob Chemother       Date:  1984-11       Impact factor: 5.790

4.  In vitro activity of LY146032 (daptomycin) against selected aerobic bacteria.

Authors:  J H Jorgensen; L A Maher; J S Redding
Journal:  Eur J Clin Microbiol       Date:  1987-02       Impact factor: 3.267

5.  In vitro activity of teichomycin compared with those of other antibiotics.

Authors:  H C Neu; P Labthavikul
Journal:  Antimicrob Agents Chemother       Date:  1983-09       Impact factor: 5.191
  5 in total
  3 in total

1.  In vitro activities of three semisynthetic amide derivatives of teicoplanin, MDL 62208, MDL 62211, and MDL 62873.

Authors:  F Biavasco; R Lupidi; P E Varaldo
Journal:  Antimicrob Agents Chemother       Date:  1992-02       Impact factor: 5.191

2.  In vitro activities of ramoplanin and four glycopeptide antibiotics against clinical isolates of Clostridium difficile.

Authors:  F Biavasco; E Manso; P E Varaldo
Journal:  Antimicrob Agents Chemother       Date:  1991-01       Impact factor: 5.191

3.  Comparative in vitro activity of the new glycopeptide SK&F 104662 against problematic gram-positive bacteria.

Authors:  F Soriano; J Zapardiel; R Fernández-Roblas
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-09       Impact factor: 3.267
  3 in total

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