Literature DB >> 27283385

Magnetic Multivalent Trehalose Glycopolymer Nanoparticles for the Detection of Mycobacteria.

Xuan Chen1, Bin Wu1, Kalana W Jayawardana1, Nanjing Hao1, H Surangi N Jayawardena2, Robert Langer2, Ana Jaklenec2, Mingdi Yan1.   

Abstract

A multivalent trehalose-grafted poly(lactic acid) is synthesized and encapsulated with iron oxide magnetic nanoparticles. The magnetic micelles interact with Mycobacterium smegmatis to form orange clusters. Very little particle interaction is found on Staphylococcus epidermidis 35984 or Escherichia coli ORN 208. The presented new approach to the detection of mycobacteria does not require molecular biology reagents or sophisticated instruments.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  glycopolymer; magnetic micelles; mycobacterium; poly(lactic acid); trehalose

Mesh：

Substances：

Year:  2016        PMID： 27283385      PMCID： PMC5242184          DOI： 10.1002/adhm.201600071

Source DB:  PubMed          Journal:  Adv Healthc Mater        ISSN： 2192-2640            Impact factor:   9.933


  31 in total

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