Literature DB >> 27280867

A knowledge base for tracking the impact of genomics on population health.

Wei Yu1, Marta Gwinn1,2, W David Dotson1, Ridgely Fisk Green1,3, Mindy Clyne4,5, Anja Wulf1,6, Scott Bowen1, Katherine Kolor1, Muin J Khoury1.   

Abstract

PURPOSE: We created an online knowledge base (the Public Health Genomics Knowledge Base (PHGKB)) to provide systematically curated and updated information that bridges population-based research on genomics with clinical and public health applications.
METHODS: Weekly horizon scanning of a wide variety of online resources is used to retrieve relevant scientific publications, guidelines, and commentaries. After curation by domain experts, links are deposited into Web-based databases.
RESULTS: PHGKB currently consists of nine component databases. Users can search the entire knowledge base or search one or more component databases directly and choose options for customizing the display of their search results.
CONCLUSION: PHGKB offers researchers, policy makers, practitioners, and the general public a way to find information they need to understand the complicated landscape of genomics and population health.Genet Med 18 12, 1312-1314.

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Year:  2016        PMID: 27280867      PMCID: PMC5133140          DOI: 10.1038/gim.2016.63

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  7 in total

1.  A navigator for human genome epidemiology.

Authors:  Wei Yu; Marta Gwinn; Melinda Clyne; Ajay Yesupriya; Muin J Khoury
Journal:  Nat Genet       Date:  2008-02       Impact factor: 38.330

2.  Charting a course for genomic medicine from base pairs to bedside.

Authors:  Eric D Green; Mark S Guyer
Journal:  Nature       Date:  2011-02-10       Impact factor: 49.962

Review 3.  Prioritizing genomic applications for action by level of evidence: a horizon-scanning method.

Authors:  W D Dotson; M P Douglas; K Kolor; A C Stewart; M S Bowen; M Gwinn; A Wulf; H M Anders; C Q Chang; M Clyne; T K Lam; S D Schully; M Marrone; W G Feero; M J Khoury
Journal:  Clin Pharmacol Ther       Date:  2014-02-19       Impact factor: 6.875

4.  The genomic applications in practice and prevention network.

Authors:  Muin J Khoury; W Gregory Feero; Michele Reyes; Toby Citrin; Andrew Freedman; Debra Leonard; Wylie Burke; Ralph Coates; Robert T Croyle; Karen Edwards; Sharon Kardia; Colleen McBride; Teri Manolio; Gurvaneet Randhawa; Rebekah Rasooly; Jeannette St Pierre; Sharon Terry
Journal:  Genet Med       Date:  2009-07       Impact factor: 8.822

Review 5.  The continuum of translation research in genomic medicine: how can we accelerate the appropriate integration of human genome discoveries into health care and disease prevention?

Authors:  Muin J Khoury; Marta Gwinn; Paula W Yoon; Nicole Dowling; Cynthia A Moore; Linda Bradley
Journal:  Genet Med       Date:  2007-10       Impact factor: 8.822

6.  GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique.

Authors:  Wei Yu; Melinda Clyne; Siobhan M Dolan; Ajay Yesupriya; Anja Wulf; Tiebin Liu; Muin J Khoury; Marta Gwinn
Journal:  BMC Bioinformatics       Date:  2008-04-22       Impact factor: 3.169

7.  Horizon scanning for translational genomic research beyond bench to bedside.

Authors:  Mindy Clyne; Sheri D Schully; W David Dotson; Michael P Douglas; Marta Gwinn; Katherine Kolor; Anja Wulf; M Scott Bowen; Muin J Khoury
Journal:  Genet Med       Date:  2014-01-09       Impact factor: 8.822

  7 in total
  11 in total

Review 1.  First Responder to Genomic Information: A Guide for Primary Care Providers.

Authors:  Susanne B Haga
Journal:  Mol Diagn Ther       Date:  2019-08       Impact factor: 4.074

Review 2.  Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors.

Authors:  Rita K Schmutzler; Björn Schmitz-Luhn; Bettina Borisch; Peter Devilee; Diana Eccles; Per Hall; Judith Balmaña; Stefania Boccia; Peter Dabrock; Günter Emons; Wolfgang Gaissmaier; Jacek Gronwald; Stefanie Houwaart; Stefan Huster; Karin Kast; Alexander Katalinic; Sabine C Linn; Sowmiya Moorthie; Paul Pharoah; Kerstin Rhiem; Tade Spranger; Dominique Stoppa-Lyonnet; Johannes Jozef Marten van Delden; Marc van den Bulcke; Christiane Woopen
Journal:  Breast Care (Basel)       Date:  2021-08-12       Impact factor: 2.268

3.  The Mechanism of Dendrobium officinale as a Treatment for Hyperlipidemia Based on Network Pharmacology and Experimental Validation.

Authors:  Lin-Zi Li; Hui-Ying Wang; Jia-Hui Huang; Kun Liu; Xiao-Jie Feng; Xi-Ming Wang; Li-Jie Zhu; Xing-Lishang He; Xiang Zheng; Hai-Long Li; Ying-Jie Dong; Bo Li; Han-Song Wu; Ning-Hua Jiang; Gui-Yuan Lv; Su-Hong Chen
Journal:  Evid Based Complement Alternat Med       Date:  2022-04-13       Impact factor: 2.650

Review 4.  The current state of implementation science in genomic medicine: opportunities for improvement.

Authors:  Megan C Roberts; Amy E Kennedy; David A Chambers; Muin J Khoury
Journal:  Genet Med       Date:  2017-01-12       Impact factor: 8.822

5.  Proposed outcomes measures for state public health genomic programs.

Authors:  Debra Lochner Doyle; Mindy Clyne; Juan L Rodriguez; Deborah L Cragun; Laura Senier; Georgia Hurst; Kee Chan; David A Chambers
Journal:  Genet Med       Date:  2018-01-04       Impact factor: 8.822

6.  Tracking human genes along the translational continuum.

Authors:  Kyubum Lee; Mindy Clyne; Wei Yu; Zhiyong Lu; Muin J Khoury
Journal:  NPJ Genom Med       Date:  2019-10-16       Impact factor: 8.617

7.  Using deep learning to identify translational research in genomic medicine beyond bench to bedside.

Authors:  Yi-Yu Hsu; Mindy Clyne; Chih-Hsuan Wei; Muin J Khoury; Zhiyong Lu
Journal:  Database (Oxford)       Date:  2019-01-01       Impact factor: 3.451

Review 8.  From Patient Engagement to Precision Oncology: Leveraging Informatics to Advance Cancer Care.

Authors:  Ashley C Griffin; Umit Topaloglu; Sean Davis; Arlene E Chung
Journal:  Yearb Med Inform       Date:  2020-08-21

9.  Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals.

Authors:  Yuqing Chen; Irfahan Kassam; Suk Hiang Lau; Jaspal S Kooner; Rory Wilson; Annette Peters; Juliane Winkelmann; John C Chambers; Vincent T Chow; Chiea Chuen Khor; Rob M van Dam; Yik-Ying Teo; Marie Loh; Xueling Sim
Journal:  Clin Epigenetics       Date:  2021-10-20       Impact factor: 6.551

Review 10.  From public health genomics to precision public health: a 20-year journey.

Authors:  Muin J Khoury; M Scott Bowen; Mindy Clyne; W David Dotson; Marta L Gwinn; Ridgely Fisk Green; Katherine Kolor; Juan L Rodriguez; Anja Wulf; Wei Yu
Journal:  Genet Med       Date:  2017-12-14       Impact factor: 8.822

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