Ryuichi Kawamoto1, Nobuyuki Ohtsuka2, Shumpei Nakamura2, Daisuke Ninomiya2, Ai Inoue2. 1. Department of Internal Medicine, Seiyo Municipal Nomura Hospital, 9-53 Nomura, Nomura-cho, Seiyo-city, Ehime, 797-1212, Japan. rykawamo@ehime.med.or.jp. 2. Department of Internal Medicine, Seiyo Municipal Nomura Hospital, 9-53 Nomura, Nomura-cho, Seiyo-city, Ehime, 797-1212, Japan.
Abstract
PURPOSE: To determine optimal cutoff values for preperitoneal fat thickness measured by ultrasonography as indicators for obesity-related disorders. METHODS: We studied 276 men aged 60 ± 13 years and 307 women aged 64 ± 11 years. Participants were consecutively enrolled from inpatients aged ≤75 years. Demographic data were collected and maximal preperitoneal fat thickness (PFTmax) and carotid intima-media thickness were evaluated on B-mode ultrasonography. Receiver operating characteristic (ROC) curve analysis was performed to determine optimal cutoff values for PFTmax. RESULTS: Multiple regression analysis using one or more obesity-related disorders as an objective variable showed that the tertile on the basis of PFTmax was a significant independent contributing factor in both men and women. Receiver operating characteristic curve analysis identified the cutoff points of 6.1 mm for PFTmax in men (sensitivity, 66.7%; specificity, 62.5%) and 8.7 mm for PFTmax in women (sensitivity, 56.6%; specificity, 63.6%) as discriminator values corresponding to the presence of one or more obesity-related disorders. Using the new criteria to diagnose visceral obesity, we found that adjusted carotid intima-media thickness was significantly higher in men and women with visceral obesity and two or more obesity-related disorders than in those without them. CONCLUSIONS: These findings suggested that PFTmax measured on ultrasonography was useful in screening for indicators of cardiovascular risk factors.
PURPOSE: To determine optimal cutoff values for preperitoneal fat thickness measured by ultrasonography as indicators for obesity-related disorders. METHODS: We studied 276 men aged 60 ± 13 years and 307 women aged 64 ± 11 years. Participants were consecutively enrolled from inpatients aged ≤75 years. Demographic data were collected and maximal preperitoneal fat thickness (PFTmax) and carotid intima-media thickness were evaluated on B-mode ultrasonography. Receiver operating characteristic (ROC) curve analysis was performed to determine optimal cutoff values for PFTmax. RESULTS: Multiple regression analysis using one or more obesity-related disorders as an objective variable showed that the tertile on the basis of PFTmax was a significant independent contributing factor in both men and women. Receiver operating characteristic curve analysis identified the cutoff points of 6.1 mm for PFTmax in men (sensitivity, 66.7%; specificity, 62.5%) and 8.7 mm for PFTmax in women (sensitivity, 56.6%; specificity, 63.6%) as discriminator values corresponding to the presence of one or more obesity-related disorders. Using the new criteria to diagnose visceral obesity, we found that adjusted carotid intima-media thickness was significantly higher in men and women with visceral obesity and two or more obesity-related disorders than in those without them. CONCLUSIONS: These findings suggested that PFTmax measured on ultrasonography was useful in screening for indicators of cardiovascular risk factors.
Authors: F F Ribeiro-Filho; A N Faria; O Kohlmann; S Ajzen; A B Ribeiro; M T Zanella; S R Ferreira Journal: Hypertension Date: 2001-09 Impact factor: 10.190
Authors: T Nakamura; K Tokunaga; I Shimomura; M Nishida; S Yoshida; K Kotani; A H Islam; Y Keno; T Kobatake; Y Nagai Journal: Atherosclerosis Date: 1994-06 Impact factor: 5.162