Literature DB >> 27278273

Gaps exist between patients' experience and clinicians' awareness of symptoms after chemotherapy: CINV and accompanying symptoms.

Sun Young Rha1, Su Kyung Song2, Chung Eun Lee2, Yeonhee Park3, Jiyeon Lee4.   

Abstract

INTRODUCTION: Correlating patients' chemotherapy-induced nausea and vomiting (CINV) experience with clinicians' understanding of the symptom severity and the patients' and clinicians' symptom management goals would aid in advancing symptom management. Identifying rankings of symptom severity after chemotherapy would help prioritizing symptom management.
OBJECTIVE: The purpose of this study was to investigate and compare patients' CINV experience and clinicians' awareness of symptoms and symptom management goals. The study also aimed to identify and compare rankings of the severity of symptoms after chemotherapy by patients and clinicians.
METHODS: A prospective observational study was conducted. Cancer patients starting the first adjuvant highly emetogenic chemotherapy (HEC) or moderately emetogenic chemotherapy (MEC) (n = 313), and oncology clinicians at two university hospitals (n = 73) in Korea participated in the study. The Multinational Association of Supportive Care in Cancer Antiemesis Tool (MAT) items and 20-symptom list were used to generate a symptom diary and survey questions. Descriptive statistics with a 95 % confidence interval and the Mann-Whitney U test were used to analyze the data.
RESULTS: In general, clinicians overestimated the patients' CINV experience. Patients' symptom experiences and clinicians' estimates only corresponded for delayed nausea after the second cycle MEC. For symptom management goals, patients aimed for absolute vomiting control and avoiding significant nausea. Patients' symptom management goals exceeded the clinicians' goals for CINV control except for the goal for delayed nausea control. Clinicians rated chemotherapy-induced nausea as the most problematic symptom followed by vomiting; however, fatigue and loss of appetite were the top rated symptoms by patients.
CONCLUSIONS: Gaps exist between patients' symptom experience and clinicians' symptom awareness. Clinicians overestimated the patients' CINV experience and set less stringent symptom control goals. Enhancing clinicians' understanding of patients' symptom experience and retargeting the CINV management goals are the next steps for advancing symptom management. Symptoms other than CINV require more attention to set symptom management priorities reflecting patient experience and clinical significance.

Entities:  

Keywords:  Chemotherapy; Nausea; Symptom management; Vomiting

Mesh:

Substances:

Year:  2016        PMID: 27278273     DOI: 10.1007/s00520-016-3295-y

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  23 in total

1.  Incidence of chemotherapy-induced nausea and vomiting in Mexico: healthcare provider predictions versus observed.

Authors:  Aura Erazo Valle; Tami Wisniewski; Jasmin Isabel Figueroa Vadillo; Thomas A Burke; Roberto Martinez Corona
Journal:  Curr Med Res Opin       Date:  2006-12       Impact factor: 2.580

2.  Impact of CINV in earlier cycles on CINV and chemotherapy regimen modification in subsequent cycles in Asia Pacific clinical practice.

Authors:  Hoon-Kyo Kim; RueyKuen Hsieh; Alexandre Chan; Shiying Yu; Baohui Han; Yunong Gao; Ana Baños; Xiaoyan Ying; Thomas A Burke; Dorothy M K Keefe
Journal:  Support Care Cancer       Date:  2014-08-21       Impact factor: 3.603

3.  On the receiving end. V: Patient perceptions of the side effects of cancer chemotherapy in 1993.

Authors:  A M Griffin; P N Butow; A S Coates; A M Childs; P M Ellis; S M Dunn; M H Tattersall
Journal:  Ann Oncol       Date:  1996-02       Impact factor: 32.976

4.  Incidence of chemotherapy-induced nausea and vomiting in Taiwan: physicians' and nurses' estimation vs. patients' reported outcomes.

Authors:  Chi-Ting Liau; Nei-Min Chu; Hsueh-Erh Liu; Robert Deuson; Jade Lien; Jen-Shi Chen
Journal:  Support Care Cancer       Date:  2005-03-16       Impact factor: 3.603

5.  Self-evaluation of Adjuvant Chemotherapy-Related Adverse Effects by Patients With Breast Cancer.

Authors:  Filippo Montemurro; Gloria Mittica; Celeste Cagnazzo; Virginia Longo; Paola Berchialla; Gianfranca Solinas; Paola Culotta; Rossella Martinello; Manuela Foresto; Simona Gallizioli; Adele Calori; Bruna Grasso; Chiara Volpone; Gisella Bertola; Gisella Parola; Giancarla Tealdi; Piero Luigi Giuliano; Massimo Aglietta; Anna Maria Ballari
Journal:  JAMA Oncol       Date:  2016-04       Impact factor: 31.777

6.  Evaluation of risk factors predicting chemotherapy-related nausea and vomiting: results from a European prospective observational study.

Authors:  Alexander Molassiotis; Matti Aapro; Mario Dicato; Pere Gascon; Sylvia A Novoa; Nicolas Isambert; Thomas A Burke; Anna Gu; Fausto Roila
Journal:  J Pain Symptom Manage       Date:  2013-09-24       Impact factor: 3.612

7.  Evaluation of risk factors predictive of nausea and vomiting with current standard-of-care antiemetic treatment: analysis of two phase III trials of aprepitant in patients receiving cisplatin-based chemotherapy.

Authors:  Paul J Hesketh; Matti Aapro; James C Street; Alexandra D Carides
Journal:  Support Care Cancer       Date:  2009-09-12       Impact factor: 3.603

8.  Changing patient perceptions of the side effects of cancer chemotherapy.

Authors:  Nadége Carelle; Estelle Piotto; Agnés Bellanger; Jerome Germanaud; Alain Thuillier; David Khayat
Journal:  Cancer       Date:  2002-07-01       Impact factor: 6.860

9.  Validation and psychometric assessment of a short clinical scale to measure chemotherapy-induced nausea and vomiting: the MASCC antiemesis tool.

Authors:  Alexander Molassiotis; Peter A Coventry; Carrie T Stricker; Caroline Clements; Beth Eaby; Luke Velders; Cynthia Rittenberg; Richard J Gralla
Journal:  J Pain Symptom Manage       Date:  2007-05-23       Impact factor: 3.612

10.  Patient perceptions of the side-effects of chemotherapy: the influence of 5HT3 antagonists.

Authors:  M de Boer-Dennert; R de Wit; P I Schmitz; J Djontono; V v Beurden; G Stoter; J Verweij
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

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  3 in total

1.  Symptom clusters during palliative chemotherapy and their influence on functioning and quality of life.

Authors:  Sun Young Rha; Jiyeon Lee
Journal:  Support Care Cancer       Date:  2016-12-28       Impact factor: 3.603

2.  Frequency of low-grade adverse events and quality of life during chemotherapy determine patients' judgement about treatment in advanced-stage thoracic cancer.

Authors:  Mark de Mol; Sabine Visser; Brenda L den Oudsten; Paul Lodder; Nico van Walree; Huub Belderbos; Joachim G Aerts
Journal:  Support Care Cancer       Date:  2019-01-28       Impact factor: 3.603

3.  Breast Cancer Patients' Perceptions of Their Experience With Chemotherapy-Induced Nausea and Vomiting and Its Impact on Quality of Life in Jeddah, Saudi Arabia.

Authors:  Ahmed B Ilyas; Reem K Bahaj; Azzam A Shaikh; Bashaer S Khawandanah; Meteb Al-Foheidi; Tagwa Y Omer
Journal:  Cureus       Date:  2020-12-12
  3 in total

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