Kazushi Numata1, Manabu Morimoto2, Tetsuo Isozaki2, Kazuya Sugimori2, Hiroyuki Oka2, Kenichi Matsuo2, Hiroshi Shimada3, Toshio Imada2, Katsuaki Tanaka2. 1. Gastroenterological Center, Yokohama City University Medical Center, 4-57 Urafune, Minami, Yokohama, Kanagawa, 232-0024, Japan. kz-numa@zero.ad.jp. 2. Gastroenterological Center, Yokohama City University Medical Center, 4-57 Urafune, Minami, Yokohama, Kanagawa, 232-0024, Japan. 3. Second Department of Surgery, Yokohama City University School of Medicine, Kanagawa, Japan.
Abstract
PURPOSE: To evaluate the usefulness of accumulation images obtained by arterial-phase contrast-enhanced harmonic grayscale ultrasonography for examining tumor vessels in focal nodular hyperplasia and other hepatic lesions. METHODS: After injecting a galactose-palmitic acid contrast agent, we used conventional contrast-enhanced harmonic grayscale ultrasonography to scan 8 focal nodular hyperplasia lesions, 21 hepatocellular carcinomas, 2 cholangiocellular carcinomas, 12 hepatic metastases, 17 hemangiomas, and 2 angiomyolipomas. We then accumulated and superimposed consecutive conventional images (accumulation images) and compared them with corresponding conventional images to evaluate serial images of hepatic tumor vessels. RESULTS: Serial tumor vessel findings obtained from accumulation images were superior to those obtained from conventional images in 51 (77%) of the 66 various hepatic lesions examined. Evidence of the spoke-wheel artery pattern in 2 of the 8 focal nodular hyperplasia lesions was equivocal in the conventional images, but accumulation images clearly depicted serial images of spoke-wheel arteries, clearly indicating a diagnosis of focal nodular hyperplasia. Accumulation images allowed the diagnosis of two additional focal nodular hyperplasia lesions that had not been correctly diagnosed as focal nodular hyperplasia from conventional images. CONCLUSION: Accumulation images obtained by arterial-phase contrast-enhanced harmonic grayscale ultrasonography are useful in evaluating hepatic tumor vessels, especially spoke-wheel arteries, which specifically indicate focal nodular hyperplasia.
PURPOSE: To evaluate the usefulness of accumulation images obtained by arterial-phase contrast-enhanced harmonic grayscale ultrasonography for examining tumor vessels in focal nodular hyperplasia and other hepatic lesions. METHODS: After injecting a galactose-palmitic acid contrast agent, we used conventional contrast-enhanced harmonic grayscale ultrasonography to scan 8 focal nodular hyperplasia lesions, 21 hepatocellular carcinomas, 2 cholangiocellular carcinomas, 12 hepatic metastases, 17 hemangiomas, and 2 angiomyolipomas. We then accumulated and superimposed consecutive conventional images (accumulation images) and compared them with corresponding conventional images to evaluate serial images of hepatic tumor vessels. RESULTS: Serial tumor vessel findings obtained from accumulation images were superior to those obtained from conventional images in 51 (77%) of the 66 various hepatic lesions examined. Evidence of the spoke-wheel artery pattern in 2 of the 8 focal nodular hyperplasia lesions was equivocal in the conventional images, but accumulation images clearly depicted serial images of spoke-wheel arteries, clearly indicating a diagnosis of focal nodular hyperplasia. Accumulation images allowed the diagnosis of two additional focal nodular hyperplasia lesions that had not been correctly diagnosed as focal nodular hyperplasia from conventional images. CONCLUSION: Accumulation images obtained by arterial-phase contrast-enhanced harmonic grayscale ultrasonography are useful in evaluating hepatic tumor vessels, especially spoke-wheel arteries, which specifically indicate focal nodular hyperplasia.
Authors: D Mathieu; M Paret; A E Mahfouz; F Caseiro-Alves; J Tran Van Nhieu; M C Anglade; A Rahmouni; N Vasile Journal: Abdom Imaging Date: 1997 Jul-Aug
Authors: E Rummeny; R Weissleder; S Sironi; D D Stark; C C Comptom; P F Hahn; S Saini; J Wittenberg; J T Ferrucci Journal: Radiology Date: 1989-05 Impact factor: 11.105