Literature DB >> 27274669

Can Time Efficient Exercise Improve Cardiometabolic Risk Factors in Type 2 Diabetes? A Pilot Study.

Anders Revdal1, Siri M Hollekim-Strand1, Charlotte B Ingul1.   

Abstract

Exercise is considered a cornerstone in the prevention and treatment of type 2 diabetes, but few individuals with type 2 diabetes exercise according to guidelines. We investigated the effect of two time efficient high intensity exercise interventions on exercise capacity, glycemic control and other cardiometabolic risk factors in patients with type 2 diabetes. Twenty-one individuals with type 2 diabetes were randomly assigned to low volume high intensity interval exercise (HIIE; 27 minutes/bout; 10x1-minute at 90 % of HRmax; n = 10) or extremely low volume sprint interval exercise (SIE; 10 minutes/bout; 2x20 seconds at maximum achievable intensity; n = 11) 3 days/week for 12 weeks. Aerobic exercise capacity (VO2peak), glycosylated hemoglobin (HbA1c), blood pressure and body composition were measured at baseline and post test. Both HIIE and SIE improved VO2peak (3.3 mL·min(-1)·kg(-1), 10.4 %), p < 0.01, and 1.4 mL·min(-1)·kg(-1) (4.6 %), p = 0.03, respectively). Only HIIE reduced body fat percentage (4.5 %, p = 0.04) and two minute heart rate recovery (11.0 bpm, p = 0.02). Neither HIIE nor SIE improved HbA1c. In conclusion, this study indicates that substantially lower exercise volumes than recommended in current guidelines can improve aerobic exercise capacity in individuals with type 2 diabetes. However, 12 weeks of time efficient high intensity exercise did not improve glycemic control, and interventions of longer duration should be investigated. Key pointsLow volume high-intensity interval exercise can improve peak oxygen uptake in previously sedentary individuals with type 2 diabetesThe weekly exercise volumes in the two intervention groups of 81 and 30 minutes respectively, is substantially lower than recommended in current exercise guidelines and could reduce the time-barrier associated with exercise among patients with type 2 diabetes.However, 12 weeks of structured, supervised low-volume exercise did not improve glycemic control, indicating a need for exercise volumes or longer intervention period.

Entities:  

Keywords:  HbA1c; Low volume exercise; VO2peak; cardiovascular risk; type 2 diabetes

Year:  2016        PMID: 27274669      PMCID: PMC4879445     

Source DB:  PubMed          Journal:  J Sports Sci Med        ISSN: 1303-2968            Impact factor:   2.988


  28 in total

1.  A meta-analysis of the factors affecting exercise-induced changes in body mass, fat mass and fat-free mass in males and females.

Authors:  D L Ballor; R E Keesey
Journal:  Int J Obes       Date:  1991-11

2.  Standards of medical care in diabetes--2014.

Authors: 
Journal:  Diabetes Care       Date:  2014-01       Impact factor: 19.112

3.  High-intensity interval exercise effectively improves cardiac function in patients with type 2 diabetes mellitus and diastolic dysfunction: a randomized controlled trial.

Authors:  Siri M Hollekim-Strand; Marit R Bjørgaas; Grethe Albrektsen; Arnt E Tjønna; Ulrik Wisløff; Charlotte B Ingul
Journal:  J Am Coll Cardiol       Date:  2014-10-21       Impact factor: 24.094

4.  Low-volume high-intensity interval training reduces hyperglycemia and increases muscle mitochondrial capacity in patients with type 2 diabetes.

Authors:  Jonathan P Little; Jenna B Gillen; Michael E Percival; Adeel Safdar; Mark A Tarnopolsky; Zubin Punthakee; Mary E Jung; Martin J Gibala
Journal:  J Appl Physiol (1985)       Date:  2011-08-25

5.  Cardiorespiratory fitness and body mass index as predictors of cardiovascular disease mortality among men with diabetes.

Authors:  Timothy S Church; Michael J LaMonte; Carolyn E Barlow; Steven N Blair
Journal:  Arch Intern Med       Date:  2005-10-10

6.  Prevalence of obesity in type 2 diabetes in secondary care: association with cardiovascular risk factors.

Authors:  C Daousi; I F Casson; G V Gill; I A MacFarlane; J P H Wilding; J H Pinkney
Journal:  Postgrad Med J       Date:  2006-04       Impact factor: 2.401

Review 7.  Cardiovascular disease in type 2 diabetes: challenge for treatment and prevention.

Authors:  M Laakso
Journal:  J Intern Med       Date:  2001-03       Impact factor: 8.989

8.  Heart rate recovery following maximal exercise testing as a predictor of cardiovascular disease and all-cause mortality in men with diabetes.

Authors:  Yiling J Cheng; Michael S Lauer; Conrad P Earnest; Timothy S Church; James B Kampert; Larry W Gibbons; Steven N Blair
Journal:  Diabetes Care       Date:  2003-07       Impact factor: 19.112

9.  Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary.

Authors:  Sheri R Colberg; Ronald J Sigal; Bo Fernhall; Judith G Regensteiner; Bryan J Blissmer; Richard R Rubin; Lisa Chasan-Taber; Ann L Albright; Barry Braun
Journal:  Diabetes Care       Date:  2010-12       Impact factor: 19.112

10.  Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.

Authors:  N Sarwar; P Gao; S R Kondapally Seshasai; R Gobin; S Kaptoge; E Di Angelantonio; E Ingelsson; D A Lawlor; E Selvin; M Stampfer; C D A Stehouwer; S Lewington; L Pennells; A Thompson; N Sattar; I R White; K K Ray; J Danesh
Journal:  Lancet       Date:  2010-06-26       Impact factor: 202.731

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  8 in total

1.  High-intensity aerobic interval training improves aerobic fitness and HbA1c among persons diagnosed with type 2 diabetes.

Authors:  Eva Maria Støa; Sondre Meling; Lill-Katrin Nyhus; Karl Magnus Mangerud; Jan Helgerud; Solfrid Bratland-Sanda; Øyvind Støren
Journal:  Eur J Appl Physiol       Date:  2017-02-03       Impact factor: 3.078

2.  Exercise/Physical Activity in Individuals with Type 2 Diabetes: A Consensus Statement from the American College of Sports Medicine.

Authors:  Jill A Kanaley; Sheri R Colberg; Matthew H Corcoran; Steven K Malin; Nancy R Rodriguez; Carlos J Crespo; John P Kirwan; Juleen R Zierath
Journal:  Med Sci Sports Exerc       Date:  2022-02-01       Impact factor: 5.411

Review 3.  The Effects of Chronic Aerobic Exercise on Cardiovascular Risk Factors in Persons with Diabetes Mellitus.

Authors:  Emily M Miele; Samuel A E Headley
Journal:  Curr Diab Rep       Date:  2017-09-12       Impact factor: 4.810

4.  Sprint interval training decreases left-ventricular glucose uptake compared to moderate-intensity continuous training in subjects with type 2 diabetes or prediabetes.

Authors:  Marja A Heiskanen; Tanja J Sjöros; Ilkka H A Heinonen; Eliisa Löyttyniemi; Mikko Koivumäki; Kumail K Motiani; Jari-Joonas Eskelinen; Kirsi A Virtanen; Juhani Knuuti; Jarna C Hannukainen; Kari K Kalliokoski
Journal:  Sci Rep       Date:  2017-09-05       Impact factor: 4.379

5.  Timing of Exercise Affects Glycemic Control in Type 2 Diabetes Patients Treated with Metformin.

Authors:  Tao Huang; Chunyan Lu; Moritz Schumann; Shenglong Le; Yifan Yang; Haihui Zhuang; Qingwei Lu; Jinsheng Liu; Petri Wiklund; Sulin Cheng
Journal:  J Diabetes Res       Date:  2018-03-29       Impact factor: 4.011

6.  Exercise capacity in diabetes mellitus is predicted by activity status and cardiac size rather than cardiac function: a case control study.

Authors:  Timothy J Roberts; Andrew T Burns; Richard J MacIsaac; Andrew I MacIsaac; David L Prior; André La Gerche
Journal:  Cardiovasc Diabetol       Date:  2018-03-23       Impact factor: 9.951

7.  Carbohydrate-Restriction with High-Intensity Interval Training: An Optimal Combination for Treating Metabolic Diseases?

Authors:  Monique E Francois; Jenna B Gillen; Jonathan P Little
Journal:  Front Nutr       Date:  2017-10-12

8.  Feasibility of procedures for a randomised pilot study of reduced exertion, high-intensity interval training (REHIT) with non-diabetic hyperglycaemia patients.

Authors:  Matthew Haines
Journal:  Pilot Feasibility Stud       Date:  2020-02-19
  8 in total

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