| Literature DB >> 27273767 |
Florence Kermen1,2, Maëllie Midroit1, Nicola Kuczewski1, Jérémy Forest1, Marc Thévenet1, Joëlle Sacquet1, Claire Benetollo3, Marion Richard1, Anne Didier1, Nathalie Mandairon1.
Abstract
Hedonic value is a dominant aspect of olfactory perception. Using optogenetic manipulation in freely behaving mice paired with immediate early gene mapping, we demonstrate that hedonic information is represented along the antero-posterior axis of the ventral olfactory bulb. Using this representation, we show that the degree of attractiveness of odors can be bidirectionally modulated by local manipulation of the olfactory bulb's neural networks in freely behaving mice.Entities:
Mesh：
Year: 2016 PMID： 27273767 DOI： 10.1038/nn.4317
Source DB: PubMed Journal: Nat Neurosci ISSN： 1097-6256 Impact factor: 24.884