Literature DB >> 27272520

Reversal of fortune: estrogen receptor-β in endometriosis.

Rosalia C M Simmen1, Angela S Kelley2.   

Abstract

Enhanced inflammation and reduced apoptosis sustain the growth of endometriotic lesions. Alterations in the expression of estrogen receptor-alpha (ERα) and estrogen receptor-beta (ERβ) accompany the conversion of resident endometrial cells within the normal uterine environment to ectopic lesions located in extrauterine sites. Recent studies highlighted in this focused review linked ERβ to dysregulation of apoptotic and inflammatory networks involving novel interacting partners in endometriosis. The elucidation of these nongenomic actions of ERβ using human cells and mouse models is an important step in understanding key regulatory pathways that are disrupted leading to disease establishment and progression.
© 2016 Society for Endocrinology.

Entities:  

Keywords:  apoptosome; endometriosis; estrogen receptor-beta; inflammation; non-genomic

Mesh：

Substances：

Year:  2016        PMID： 27272520      PMCID： PMC4973618          DOI： 10.1530/JME-16-0080

Source DB:  PubMed          Journal:  J Mol Endocrinol        ISSN： 0952-5041            Impact factor:   5.098


  21 in total

1.  A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis.

Authors:  Sang Jun Han; Shannon M Hawkins; Khurshida Begum; Sung Yun Jung; Ertug Kovanci; Jun Qin; John P Lydon; Francesco J DeMayo; Bert W O'Malley
Journal:  Nat Med       Date:  2012-07       Impact factor: 53.440

2.  Cloning of a novel receptor expressed in rat prostate and ovary.

Authors:  G G Kuiper; E Enmark; M Pelto-Huikko; S Nilsson; J A Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

Review 3.  Pathogenesis and pathophysiology of endometriosis.

Authors:  Richard O Burney; Linda C Giudice
Journal:  Fertil Steril       Date:  2012-07-20       Impact factor: 7.329

4.  Role of estrogen receptor signaling required for endometriosis-like lesion establishment in a mouse model.

Authors:  Katherine A Burns; Karina F Rodriguez; Sylvia C Hewitt; Kyathanahalli S Janardhan; Steven L Young; Kenneth S Korach
Journal:  Endocrinology       Date:  2012-06-14       Impact factor: 4.736

5.  Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis.

Authors:  Yuechao Zhao; Ping Gong; Yiru Chen; Jerome C Nwachukwu; Sathish Srinivasan; CheMyong Ko; Milan K Bagchi; Robert N Taylor; Kenneth S Korach; Kendall W Nettles; John A Katzenellenbogen; Benita S Katzenellenbogen
Journal:  Sci Transl Med       Date:  2015-01-21       Impact factor: 17.956

Review 6.  The intersection of cell death and inflammasome activation.

Authors:  James E Vince; John Silke
Journal:  Cell Mol Life Sci       Date:  2016-04-11       Impact factor: 9.261

7.  Krüppel-like factor 9 deficiency in uterine endometrial cells promotes ectopic lesion establishment associated with activated notch and hedgehog signaling in a mouse model of endometriosis.

Authors:  Melissa E Heard; Christian D Simmons; Frank A Simmen; Rosalia C M Simmen
Journal:  Endocrinology       Date:  2014-01-29       Impact factor: 4.736

8.  Estrogen Receptor β Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis.

Authors:  Sang Jun Han; Sung Yun Jung; San-Pin Wu; Shannon M Hawkins; Mi Jin Park; Satoru Kyo; Jun Qin; John P Lydon; Sophia Y Tsai; Ming-Jer Tsai; Francesco J DeMayo; Bert W O'Malley
Journal:  Cell       Date:  2015-11-05       Impact factor: 41.582

9.  Peritoneal fluid macrophages in endometriosis: correlation between the expression of estrogen receptors and inflammation.

Authors:  Paola Montagna; Silvia Capellino; Barbara Villaggio; Valentino Remorgida; Nicola Ragni; Maurizio Cutolo; Simone Ferrero
Journal:  Fertil Steril       Date:  2007-06-04       Impact factor: 7.329

10.  A novel mouse model of endometriosis mimics human phenotype and reveals insights into the inflammatory contribution of shed endometrium.

Authors:  Erin Greaves; Fiona L Cousins; Alison Murray; Arantza Esnal-Zufiaurre; Amelie Fassbender; Andrew W Horne; Philippa T K Saunders
Journal:  Am J Pathol       Date:  2014-06-05       Impact factor: 4.307
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  11 in total

1.  Estrogen is essential but not sufficient to induce endometriosis.

Authors:  Mosami Galvankar; Neha Singh; Deepak Modi
Journal:  J Biosci       Date:  2017-06       Impact factor: 1.826

2.  Spatial and temporal changes in the expression of steroid hormone receptors in mouse model of endometriosis.

Authors:  Anuradha Mishra; Mosami Galvankar; Neha Singh; Deepak Modi
Journal:  J Assist Reprod Genet       Date:  2020-03-09       Impact factor: 3.412

Review 3.  Role of inflammation in benign gynecologic disorders: from pathogenesis to novel therapies†.

Authors:  Abdelrahman AlAshqar; Lauren Reschke; Gregory W Kirschen; Mostafa A Borahay
Journal:  Biol Reprod       Date:  2021-07-02       Impact factor: 4.285

4.  Anti-endometriosis Mechanism of Jiawei Foshou San Based on Network Pharmacology.

Authors:  Yi Chen; Jiahui Wei; Ying Zhang; Wenwei Sun; Zhuoheng Li; Qin Wang; Xiaoyu Xu; Cong Li; Panhong Li
Journal:  Front Pharmacol       Date:  2018-07-26       Impact factor: 5.810

5.  Abnormally located SSEA1+/SOX9+ endometrial epithelial cells with a basalis-like phenotype in the eutopic functionalis layer may play a role in the pathogenesis of endometriosis.

Authors:  D K Hapangama; J Drury; L Da Silva; H Al-Lamee; A Earp; A J Valentijn; D P Edirisinghe; P A Murray; A T Fazleabas; C E Gargett
Journal:  Hum Reprod       Date:  2019-01-01       Impact factor: 6.918

6.  Betulinic Acid Inhibits Endometriosis Through Suppression of Estrogen Receptor β Signaling Pathway.

Authors:  Dongfang Xiang; Min Zhao; Xiaofan Cai; Yongxia Wang; Lei Zhang; Helen Yao; Min Liu; Huan Yang; Mingtao Xu; Huilin Li; Huijuan Peng; Min Wang; Xuefang Liang; Ling Li; Paul Yao
Journal:  Front Endocrinol (Lausanne)       Date:  2020-12-10       Impact factor: 5.555

Review 7.  Estrogen- and Progesterone (P4)-Mediated Epigenetic Modifications of Endometrial Stromal Cells (EnSCs) and/or Mesenchymal Stem/Stromal Cells (MSCs) in the Etiopathogenesis of Endometriosis.

Authors:  Dariusz Szukiewicz; Aleksandra Stangret; Carmen Ruiz-Ruiz; Enrique G Olivares; Olga Soriţău; Sergiu Suşman; Grzegorz Szewczyk
Journal:  Stem Cell Rev Rep       Date:  2021-01-07       Impact factor: 5.739

Review 8.  Rodent Models of Experimental Endometriosis: Identifying Mechanisms of Disease and Therapeutic Targets.

Authors:  Kaylon L Bruner-Tran; Shilpa Mokshagundam; Jennifer L Herington; Tianbing Ding; Kevin G Osteen
Journal:  Curr Womens Health Rev       Date:  2018-06

Review 9.  Regulation of Inflammation Pathways and Inflammasome by Sex Steroid Hormones in Endometriosis.

Authors:  Elizabeth García-Gómez; Edgar Ricardo Vázquez-Martínez; Christian Reyes-Mayoral; Oliver Paul Cruz-Orozco; Ignacio Camacho-Arroyo; Marco Cerbón
Journal:  Front Endocrinol (Lausanne)       Date:  2020-01-29       Impact factor: 5.555

Review 10.  The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights.

Authors:  Antonio Simone Laganà; Simone Garzon; Martin Götte; Paola Viganò; Massimo Franchi; Fabio Ghezzi; Dan C Martin
Journal:  Int J Mol Sci       Date:  2019-11-10       Impact factor: 5.923
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