| Literature DB >> 22819144 |
Richard O Burney1, Linda C Giudice.
Abstract
Originally described over three hundred years ago, endometriosis is classically defined by the presence of endometrial glands and stroma in extrauterine locations. Endometriosis is an inflammatory, estrogen-dependent condition associated with pelvic pain and infertility. This work reviews the disease process from theories regarding origin to the molecular basis for disease sequelae. A thorough understanding of the histopathogenesis and pathophysiology of endometriosis is essential to the development of novel diagnostic and treatment approaches for this debilitating condition.Entities:
Mesh:
Year: 2012 PMID: 22819144 PMCID: PMC3836682 DOI: 10.1016/j.fertnstert.2012.06.029
Source DB: PubMed Journal: Fertil Steril ISSN: 0015-0282 Impact factor: 7.329