Literature DB >> 27271555

Exploring substrate scope and stereoselectivity of P450 peroxygenase OleTJE in olefin-forming oxidative decarboxylation.

Jian-Bo Wang1, Richard Lonsdale1, Manfred T Reetz1.   

Abstract

As recently reported, the olefin-forming oxidative decarboxylation of straight-chain C4-C22 carboxylic acids catalyzed by P450 peroxygenase OleTJE constitutes a mild alkene synthesis. The present study shows that structurally different carboxylic acids are also accepted, including those that generate di-substituted olefins. Exploratory mutational experiments lead to increased trans-selectivity.

Entities:  

Year:  2016        PMID： 27271555     DOI： 10.1039/c6cc04345c

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

Review 1.  Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.

Authors:  Xiongyi Huang; John T Groves
Journal:  Chem Rev       Date:  2017-12-29       Impact factor: 60.622

2.  The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry.

Authors:  Chun H Hsieh; Xiongyi Huang; José A Amaya; Cooper D Rutland; Carson L Keys; John T Groves; Rachel N Austin; Thomas M Makris
Journal:  Biochemistry       Date:  2017-06-26       Impact factor: 3.162

3.  In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases.

Authors:  Huifang Xu; Linlin Ning; Wenxia Yang; Bo Fang; Cong Wang; Yun Wang; Jian Xu; Severine Collin; Frederic Laeuffer; Laurent Fourage; Shengying Li
Journal:  Biotechnol Biofuels       Date:  2017-09-07       Impact factor: 6.040

Review 4.  Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C-H activation.

Authors:  Xiongyi Huang; John T Groves
Journal:  J Biol Inorg Chem       Date:  2016-12-01       Impact factor: 3.358

5.  Mutagenesis and redox partners analysis of the P450 fatty acid decarboxylase OleTJE.

Authors:  Bo Fang; Huifang Xu; Yi Liu; Fengxia Qi; Wei Zhang; Hui Chen; Cong Wang; Yilin Wang; Wenxia Yang; Shengying Li
Journal:  Sci Rep       Date:  2017-03-09       Impact factor: 4.379

6.  Different Behaviors of a Substrate in P450 Decarboxylase and Hydroxylase Reveal Reactivity-Enabling Actors.

Authors:  Vivek S Bharadwaj; Seonah Kim; Michael T Guarnieri; Michael F Crowley
Journal:  Sci Rep       Date:  2018-08-27       Impact factor: 4.379

Review 7.  Biocatalytic Oxidation Reactions: A Chemist's Perspective.

Authors:  JiaJia Dong; Elena Fernández-Fueyo; Frank Hollmann; Caroline E Paul; Milja Pesic; Sandy Schmidt; Yonghua Wang; Sabry Younes; Wuyuan Zhang
Journal:  Angew Chem Int Ed Engl       Date:  2018-07-03       Impact factor: 15.336

8.  Biochemical characterization of three new α-olefin-producing P450 fatty acid decarboxylases with a halophilic property.

Authors:  Yuanyuan Jiang; Zhong Li; Cong Wang; Yongjin J Zhou; Huifang Xu; Shengying Li
Journal:  Biotechnol Biofuels       Date:  2019-04-08       Impact factor: 6.040

9.  Production of Propene from n-Butanol: A Three-Step Cascade Utilizing the Cytochrome P450 Fatty Acid Decarboxylase OleTJE.

Authors:  Daniel Bauer; Ioannis Zachos; Volker Sieber
Journal:  Chembiochem       Date:  2020-08-05       Impact factor: 3.164

10.  A Photoclick-Based High-Throughput Screening for the Directed Evolution of Decarboxylase OleT.

Authors:  Ulrich Markel; Pia Lanvers; Daniel F Sauer; Malte Wittwer; Gaurao V Dhoke; Mehdi D Davari; Johannes Schiffels; Ulrich Schwaneberg
Journal:  Chemistry       Date:  2020-12-09       Impact factor: 5.020
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