Literature DB >> 27268311

Epidural Spinal Cord Stimulation: A Novel Therapy in the Treatment of Restless Legs Syndrome.

Marshall T Holland1, Leigh A Rettenmaier1, Oliver E Flouty1, Teri R Thomsen2, Nivedita U Jerath2, Chandan G Reddy3.   

Abstract

BACKGROUND: We report a unique finding of a patient whose restless legs syndrome (RLS) symptoms abated after the placement of a spinal cord stimulator for chronic neuropathic pain. RLS is a common disorder, with many patients unable to find sufficient relief from their symptoms. CASE DESCRIPTION: A patient diagnosed with neuropathic pain who also suffered from RLS symptoms despite medication therapy underwent implantation of a spinal cord stimulator after a successful trial. This patient was interviewed formally about his RLS symptoms immediately before his procedure and at 6 weeks, 6 months, and 2.5 years after the procedure. The patient also completed the International Restless Legs Syndrome Scale questionnaire to objectively quantify the severity of his symptoms. Finally, the patient kept a 5-day journal detailing when the stimulator was in use. The patient reported subjective symptomatic improvement in his RLS symptoms with improved sleep quality and quantity, in addition to improvement in his back pain. The patient's score on the International Restless Legs Syndrome Scale improved after implantation from 33 to 0 on a 40-point scale. Moreover, when asked to keep a journal record of his stimulator use, the patient noted that he only used the stimulator before going to bed to help his RLS symptoms and no longer required any medication for his previous RLS symptoms.
CONCLUSIONS: Epidural stimulation may be an additional, alternative, or novel therapy in the treatment of RLS.
Copyright © 2016. Published by Elsevier Inc.

Entities:  

Keywords:  Epidural; Failed back syndrome; Periodic limb movements; Restless legs syndrome; Spinal cord stimulation

Mesh:

Year:  2016        PMID: 27268311     DOI: 10.1016/j.wneu.2016.05.077

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  2 in total

1.  Femoral vascular conductance and peroneal muscle sympathetic nerve activity responses to acute epidural spinal cord stimulation in humans.

Authors:  Seth W Holwerda; Marshall T Holland; Chandan G Reddy; Gary L Pierce
Journal:  Exp Physiol       Date:  2018-05-05       Impact factor: 2.969

2.  Noninvasive neuromodulation reduces symptoms of restless legs syndrome.

Authors:  Mark J Buchfuhrer; Fiona C Baker; Haramandeep Singh; Viktoriia Kolotovska; Bahman Adlou; Harnadar Anand; Massimiliano de Zambotti; Mehvish Ismail; Shriram Raghunathan; Jonathan D Charlesworth
Journal:  J Clin Sleep Med       Date:  2021-08-01       Impact factor: 4.324

  2 in total

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